Cargando…

Progress of Interference of Traditional Chinese Medicine on Cirrhosis Treated with Bone Marrow Mesenchymal Stem Cells

Transplantation of bone marrow mesenchymal stem cells has attracted more and more attention as a regenerative therapy for the treatment of liver diseases. A large number of studies have shown that this kind of cells can inhibit the activation of hepatic stellate cells and regulate tissue homeostasis...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yaxin, Zhang, Huicun, Wang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131131/
https://www.ncbi.nlm.nih.gov/pubmed/34055009
http://dx.doi.org/10.1155/2021/5569274
_version_ 1783694653159112704
author Wang, Yaxin
Zhang, Huicun
Wang, Hongbing
author_facet Wang, Yaxin
Zhang, Huicun
Wang, Hongbing
author_sort Wang, Yaxin
collection PubMed
description Transplantation of bone marrow mesenchymal stem cells has attracted more and more attention as a regenerative therapy for the treatment of liver diseases. A large number of studies have shown that this kind of cells can inhibit the activation of hepatic stellate cells and regulate tissue homeostasis and immune system via a variety of ways. Meanwhile, bone marrow mesenchymal stem cells can inhibit apoptosis of hepatocyte, improve liver function, and reduce inflammation through multiple pathways. These cells have a broad prospect in the treatment of liver cirrhosis. At present, there are many studies on the specific mechanism of bone marrow mesenchymal stem cells transplantation in the treatment of liver cirrhosis. This paper reviews the pathogenesis of liver cirrhosis and the mechanism of bone marrow mesenchymal stem cells transplantation in the treatment of liver cirrhosis, discusses the effectiveness of traditional Chinese medicine method in enhancing the efficacy of bone marrow mesenchymal stem cells transplantation, and looks forward to its application prospect in the future.
format Online
Article
Text
id pubmed-8131131
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-81311312021-05-27 Progress of Interference of Traditional Chinese Medicine on Cirrhosis Treated with Bone Marrow Mesenchymal Stem Cells Wang, Yaxin Zhang, Huicun Wang, Hongbing Evid Based Complement Alternat Med Review Article Transplantation of bone marrow mesenchymal stem cells has attracted more and more attention as a regenerative therapy for the treatment of liver diseases. A large number of studies have shown that this kind of cells can inhibit the activation of hepatic stellate cells and regulate tissue homeostasis and immune system via a variety of ways. Meanwhile, bone marrow mesenchymal stem cells can inhibit apoptosis of hepatocyte, improve liver function, and reduce inflammation through multiple pathways. These cells have a broad prospect in the treatment of liver cirrhosis. At present, there are many studies on the specific mechanism of bone marrow mesenchymal stem cells transplantation in the treatment of liver cirrhosis. This paper reviews the pathogenesis of liver cirrhosis and the mechanism of bone marrow mesenchymal stem cells transplantation in the treatment of liver cirrhosis, discusses the effectiveness of traditional Chinese medicine method in enhancing the efficacy of bone marrow mesenchymal stem cells transplantation, and looks forward to its application prospect in the future. Hindawi 2021-05-11 /pmc/articles/PMC8131131/ /pubmed/34055009 http://dx.doi.org/10.1155/2021/5569274 Text en Copyright © 2021 Yaxin Wang et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Wang, Yaxin
Zhang, Huicun
Wang, Hongbing
Progress of Interference of Traditional Chinese Medicine on Cirrhosis Treated with Bone Marrow Mesenchymal Stem Cells
title Progress of Interference of Traditional Chinese Medicine on Cirrhosis Treated with Bone Marrow Mesenchymal Stem Cells
title_full Progress of Interference of Traditional Chinese Medicine on Cirrhosis Treated with Bone Marrow Mesenchymal Stem Cells
title_fullStr Progress of Interference of Traditional Chinese Medicine on Cirrhosis Treated with Bone Marrow Mesenchymal Stem Cells
title_full_unstemmed Progress of Interference of Traditional Chinese Medicine on Cirrhosis Treated with Bone Marrow Mesenchymal Stem Cells
title_short Progress of Interference of Traditional Chinese Medicine on Cirrhosis Treated with Bone Marrow Mesenchymal Stem Cells
title_sort progress of interference of traditional chinese medicine on cirrhosis treated with bone marrow mesenchymal stem cells
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131131/
https://www.ncbi.nlm.nih.gov/pubmed/34055009
http://dx.doi.org/10.1155/2021/5569274
work_keys_str_mv AT wangyaxin progressofinterferenceoftraditionalchinesemedicineoncirrhosistreatedwithbonemarrowmesenchymalstemcells
AT zhanghuicun progressofinterferenceoftraditionalchinesemedicineoncirrhosistreatedwithbonemarrowmesenchymalstemcells
AT wanghongbing progressofinterferenceoftraditionalchinesemedicineoncirrhosistreatedwithbonemarrowmesenchymalstemcells