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Early nucleolar responses differentiate mechanisms of cell death induced by oxaliplatin and cisplatin

Recent reports provide evidence that the platinum chemotherapeutic oxaliplatin causes cell death via ribosome biogenesis stress, while cisplatin causes cell death via the DNA damage response (DDR). Underlying differences in mechanisms that might initiate disparate routes to cell death by these two b...

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Detalles Bibliográficos
Autores principales: Sutton, Emily C., DeRose, Victoria J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131322/
https://www.ncbi.nlm.nih.gov/pubmed/33819479
http://dx.doi.org/10.1016/j.jbc.2021.100633

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