Nociceptive sensory neurons promote CD8 T cell responses to HSV-1 infection

Host protection against cutaneous herpes simplex virus 1 (HSV-1) infection relies on the induction of a robust adaptive immune response. Here, we show that Nav(1.8)(+) sensory neurons, which are involved in pain perception, control the magnitude of CD8 T cell priming and expansion in HSV-1-infected...

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Detalles Bibliográficos
Autores principales: Filtjens, Jessica, Roger, Anais, Quatrini, Linda, Wieduwild, Elisabeth, Gouilly, Jordi, Hoeffel, Guillaume, Rossignol, Rafaëlle, Daher, Clara, Debroas, Guilhaume, Henri, Sandrine, Jones, Claerwen M., Malissen, Bernard, Mackay, Laura K., Moqrich, Aziz, Carbone, Francis R., Ugolini, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131384/
https://www.ncbi.nlm.nih.gov/pubmed/34006861
http://dx.doi.org/10.1038/s41467-021-22841-6

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