Case Report: Infective Endocarditis Caused by Aspergillus flavus in a Hemodialysis Patient

Fungal endocarditis (FE) is a rare but fatal disease. The incidence of infective endocarditis (IE) in hemodialysis patients with catheters is thought to be obviously higher than that in the general population. We reported a case of IE caused by Aspergillus flavus (A. flavus) in a 36-year-old woman o...

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Autores principales: Dai, Tingting, Hu, Qinghua, Xie, Zhongshang, Li, Chunhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131528/
https://www.ncbi.nlm.nih.gov/pubmed/34026787
http://dx.doi.org/10.3389/fmed.2021.655640
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author Dai, Tingting
Hu, Qinghua
Xie, Zhongshang
Li, Chunhui
author_facet Dai, Tingting
Hu, Qinghua
Xie, Zhongshang
Li, Chunhui
author_sort Dai, Tingting
collection PubMed
description Fungal endocarditis (FE) is a rare but fatal disease. The incidence of infective endocarditis (IE) in hemodialysis patients with catheters is thought to be obviously higher than that in the general population. We reported a case of IE caused by Aspergillus flavus (A. flavus) in a 36-year-old woman on hemodialysis. Because the blood cultures were persistently negative, so we used mNGS (Metagenomic next generation sequencing) for early clinical diagnosis. After treatment with voriconazole, the patient's condition improved rapidly. She continued oral voriconazole treatment 1 year after discharge and is in good condition. The diagnosis and treatment strategies of FE in hemodialysis patients were discussed.
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spelling pubmed-81315282021-05-20 Case Report: Infective Endocarditis Caused by Aspergillus flavus in a Hemodialysis Patient Dai, Tingting Hu, Qinghua Xie, Zhongshang Li, Chunhui Front Med (Lausanne) Medicine Fungal endocarditis (FE) is a rare but fatal disease. The incidence of infective endocarditis (IE) in hemodialysis patients with catheters is thought to be obviously higher than that in the general population. We reported a case of IE caused by Aspergillus flavus (A. flavus) in a 36-year-old woman on hemodialysis. Because the blood cultures were persistently negative, so we used mNGS (Metagenomic next generation sequencing) for early clinical diagnosis. After treatment with voriconazole, the patient's condition improved rapidly. She continued oral voriconazole treatment 1 year after discharge and is in good condition. The diagnosis and treatment strategies of FE in hemodialysis patients were discussed. Frontiers Media S.A. 2021-05-05 /pmc/articles/PMC8131528/ /pubmed/34026787 http://dx.doi.org/10.3389/fmed.2021.655640 Text en Copyright © 2021 Dai, Hu, Xie and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Dai, Tingting
Hu, Qinghua
Xie, Zhongshang
Li, Chunhui
Case Report: Infective Endocarditis Caused by Aspergillus flavus in a Hemodialysis Patient
title Case Report: Infective Endocarditis Caused by Aspergillus flavus in a Hemodialysis Patient
title_full Case Report: Infective Endocarditis Caused by Aspergillus flavus in a Hemodialysis Patient
title_fullStr Case Report: Infective Endocarditis Caused by Aspergillus flavus in a Hemodialysis Patient
title_full_unstemmed Case Report: Infective Endocarditis Caused by Aspergillus flavus in a Hemodialysis Patient
title_short Case Report: Infective Endocarditis Caused by Aspergillus flavus in a Hemodialysis Patient
title_sort case report: infective endocarditis caused by aspergillus flavus in a hemodialysis patient
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131528/
https://www.ncbi.nlm.nih.gov/pubmed/34026787
http://dx.doi.org/10.3389/fmed.2021.655640
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