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Genetic pathways regulating hematopoietic lineage speciation: Factorial latent variable model analysis of single cell transcriptome

Genetic pathways regulating hematopoietic lineage commitment at critical stages of development remain incompletely characterized.  To better delineate genetic sources of variability regulating cellular speciation during steady-state hematopoiesis, we applied a factorial single-cell latent variable m...

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Detalles Bibliográficos
Autores principales: Liu, Zhaoyan, Zhu, Wei, Gnatenko, Dmitri V., Nesbitt, Natasha M., Bahou, Wadie F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131567/
https://www.ncbi.nlm.nih.gov/pubmed/34026977
http://dx.doi.org/10.1016/j.dib.2021.107080