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D614G substitution at the hinge region enhances the stability of trimeric SARS-CoV-2 spike protein
Mutations in the spike protein of SARS-CoV-2 are the major causes for the modulation of ongoing COVID-19 infection. Currently, the D614G substitution in the spike protein has become dominant worldwide. It is associated with higher infectivity than the ancestral (D614)variant. We demonstrate using Ga...
Autores principales: | Yazhini, Arangasamy, Sidhanta, Das Swayam Prakash, Srinivasan, Narayanaswamy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131580/ https://www.ncbi.nlm.nih.gov/pubmed/34092964 http://dx.doi.org/10.6026/97320630017439 |
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