TRPV1 alleviates osteoarthritis by inhibiting M1 macrophage polarization via Ca(2+)/CaMKII/Nrf2 signaling pathway

Osteoarthritis (OA) is the major course of joint deterioration, in which M1 macrophage-driven synovitis exacerbates the pathological process. However, precise therapies for M1 macrophage to decrease synovitis and attenuate OA progression have been scarcely proposed. Transient receptor potential vani...

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Detalles Bibliográficos
Autores principales: Lv, Zhongyang, Xu, Xingquan, Sun, Ziying, Yang, Yannick Xiaofan, Guo, Hu, Li, Jiawei, Sun, Kuoyang, Wu, Rui, Xu, Jia, Jiang, Qing, Ikegawa, Shiro, Shi, Dongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131608/
https://www.ncbi.nlm.nih.gov/pubmed/34006826
http://dx.doi.org/10.1038/s41419-021-03792-8

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