Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens

There is urgent need for new drug regimens that more rapidly cure tuberculosis (TB). Existing TB drugs and regimens vary in treatment-shortening activity, but the molecular basis of these differences is unclear, and no existing assay directly quantifies the ability of a drug or regimen to shorten tr...

Descripción completa

Detalles Bibliográficos
Autores principales: Walter, Nicholas D., Born, Sarah E. M., Robertson, Gregory T., Reichlen, Matthew, Dide-Agossou, Christian, Ektnitphong, Victoria A., Rossmassler, Karen, Ramey, Michelle E., Bauman, Allison A., Ozols, Victor, Bearrows, Shelby C., Schoolnik, Gary, Dolganov, Gregory, Garcia, Benjamin, Musisi, Emmanuel, Worodria, William, Huang, Laurence, Davis, J. Lucian, Nguyen, Nhung V., Nguyen, Hung V., Nguyen, Anh T. V., Phan, Ha, Wilusz, Carol, Podell, Brendan K., Sanoussi, N’ Dira, de Jong, Bouke C., Merle, Corinne S., Affolabi, Dissou, McIlleron, Helen, Garcia-Cremades, Maria, Maidji, Ekaterina, Eshun-Wilson, Franceen, Aguilar-Rodriguez, Brandon, Karthikeyan, Dhuvarakesh, Mdluli, Khisimuzi, Bansbach, Cathy, Lenaerts, Anne J., Savic, Radojka M., Nahid, Payam, Vásquez, Joshua J., Voskuil, Martin I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131613/
https://www.ncbi.nlm.nih.gov/pubmed/34006838
http://dx.doi.org/10.1038/s41467-021-22833-6

Ejemplares similares

Ejemplares similares