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Guiding functions of the C-terminal domain of topoisomerase IIα advance mitotic chromosome assembly
Topoisomerase II (topo II) is one of the six proteins essential for mitotic chromatid reconstitution in vitro. It is not fully understood, however, mechanistically how this enzyme regulates this process. In an attempt to further refine the reconstitution assay, we have found that chromosomal binding...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131626/ https://www.ncbi.nlm.nih.gov/pubmed/34006877 http://dx.doi.org/10.1038/s41467-021-23205-w |