Nuclear organisation and replication timing are coupled through RIF1–PP1 interaction

Three-dimensional genome organisation and replication timing are known to be correlated, however, it remains unknown whether nuclear architecture overall plays an instructive role in the replication-timing programme and, if so, how. Here we demonstrate that RIF1 is a molecular hub that co-regulates...

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Detalles Bibliográficos
Autores principales: Gnan, Stefano, Flyamer, Ilya M., Klein, Kyle N., Castelli, Eleonora, Rapp, Alexander, Maiser, Andreas, Chen, Naiming, Weber, Patrick, Enervald, Elin, Cardoso, M. Cristina, Bickmore, Wendy A., Gilbert, David M., Buonomo, Sara C. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131703/
https://www.ncbi.nlm.nih.gov/pubmed/34006872
http://dx.doi.org/10.1038/s41467-021-22899-2

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