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Downregulation of miR-218 by porcine reproductive and respiratory syndrome virus facilitates viral replication via inhibition of type I interferon responses

Porcine reproductive and respiratory syndrome virus (PRRSV) is a devastating pathogen in the swine industry worldwide. miRNAs are reported to be involved in virus–host interaction. Here, we used high-throughput sequencing and miRNA inhibitors to screen possible miRNAs that can inhibit PRRSV infectio...

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Detalles Bibliográficos
Autores principales: Zhang, Lin, Zhang, Lu, Pan, Yu, Gao, Junxin, Xu, Yunfei, Li, Xi, Tian, Zhijun, Chen, Hongyan, Wang, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131720/
https://www.ncbi.nlm.nih.gov/pubmed/33887325
http://dx.doi.org/10.1016/j.jbc.2021.100683