Obatoclax, the pan-Bcl-2 inhibitor sensitizes hepatocellular carcinoma cells to promote the anti-tumor efficacy in combination with immune checkpoint blockade

Bcl-2 family proteins play critical roles in regulating lymphocyte development and maintain homeostasis, and have also been proved to be involved in various cancer types development. However, the role of Bcl-2 in hepatocellular carcinoma (HCC) development has not been clearly studied. Here, we repor...

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Detalles Bibliográficos
Autores principales: Li, Jingye, Xu, Jinrong, Li, Zhibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131730/
https://www.ncbi.nlm.nih.gov/pubmed/33975180
http://dx.doi.org/10.1016/j.tranon.2021.101116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131730/
https://www.ncbi.nlm.nih.gov/pubmed/33975180
http://dx.doi.org/10.1016/j.tranon.2021.101116

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