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STAT3 determines IL-4 signalling outcomes in naïve T cells

IL-4 production is associated with low-avidity, poorly cytotoxic T cell induction that contributes to viral immune evasion and the failure of T cell-based vaccines. Yet, the precise mechanisms that regulate IL-4 signalling in T cells remain elusive. Mounting evidence indicates that cells can dynamic...

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Detalles Bibliográficos
Autores principales:	Deimel, Lachlan P., Li, Zheyi, Roy, Sreeja, Ranasinghe, Charani
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131749/ https://www.ncbi.nlm.nih.gov/pubmed/34006897 http://dx.doi.org/10.1038/s41598-021-89860-7

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