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Smoothened inhibition leads to decreased cell proliferation and suppressed tissue fibrosis in the development of benign prostatic hyperplasia

Benign prostatic hyperplasia (BPH) is a common disease in aging males. It has been proven that the Hedgehog (HH) is implied as an effective and fundamental regulatory growth factor signal for organogenesis, homeostasis, and regeneration. Smoothened (SMO), as the major control point of HH signals, ac...

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Detalles Bibliográficos
Autores principales:	Liu, Jianmin, Yin, Jing, Chen, Ping, Liu, Daoquan, He, Weixiang, Li, Yan, Li, Mingzhou, Fu, Xun, Zeng, Guang, Guo, Yuming, Wang, Xinghuan, DiSanto, Michael E., Zhang, Xinhua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131753/ https://www.ncbi.nlm.nih.gov/pubmed/34006832 http://dx.doi.org/10.1038/s41420-021-00501-4

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