IL-4 inhibits regulatory T cells differentiation by HDAC9-mediated epigenetic regulation

Regulatory T cells play a crucial role in orchestrating immune response and maintaining immune tolerance, and the expression of the Foxp3 gene is indispensable to the differentiation of regulatory T cells. IL-4 shows strong inhibitory effects on Foxp3 expression and regulatory T cells differentiatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Cui, Jikai, Xu, Heng, Yu, Jizhang, Li, Yuan, Chen, Zhang, Zou, Yanqiang, Zhang, Xi, Du, Yifan, Xia, Jiahong, Wu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131756/
https://www.ncbi.nlm.nih.gov/pubmed/34006836
http://dx.doi.org/10.1038/s41419-021-03769-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131756/
https://www.ncbi.nlm.nih.gov/pubmed/34006836
http://dx.doi.org/10.1038/s41419-021-03769-7

Ejemplares similares