IL-21 Is an Accomplice of PD-L1 in the Induction of PD-1-Dependent Treg Generation in Head and Neck Cancer

Regulatory T cells (Tregs) are immunosuppressive cells involved in antitumor immunity. However, the regulation of Treg generation by inflammation in the tumor microenvironment has not been carefully investigated. Here, we demonstrated that IL-21-polarized inflammation was enriched in the tumor micro...

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Detalles Bibliográficos
Autores principales: Zhao, Yi, Zhang, Zhiyu, Lei, Wenbin, Wei, Yi, Ma, Renqiang, Wen, Yihui, Wei, Fanqin, Fan, Jun, Xu, Yang, Chen, Lin, Lyu, Kexing, Lin, Hanqing, Wen, Weiping, Sun, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131831/
https://www.ncbi.nlm.nih.gov/pubmed/34026621
http://dx.doi.org/10.3389/fonc.2021.648293

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