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Targeting Parthanatos in Ischemic Stroke

Parthanatos is a cell death signaling pathway in which excessive oxidative damage to DNA leads to over-activation of poly(ADP-ribose) polymerase (PARP). PARP then generates the formation of large poly(ADP-ribose) polymers that induce the release of apoptosis-inducing factor from the outer mitochondr...

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Detalles Bibliográficos
Autores principales:	Koehler, Raymond C., Dawson, Valina L., Dawson, Ted M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131834/ https://www.ncbi.nlm.nih.gov/pubmed/34025565 http://dx.doi.org/10.3389/fneur.2021.662034

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