Cargando…

Combination of Wogonin and Artesunate Exhibits Synergistic anti-Hepatocellular Carcinoma Effect by Increasing DNA-Damage-Inducible Alpha, Tumor Necrosis Factor α and Tumor Necrosis Factor Receptor-Associated Factor 3-mediated Apoptosis

Hepatocellular carcinoma (HCC) is difficult to treat, and is the second leading cause of cancer-related death worldwide. This study aimed to examine whether combination of wogonin and artesunate exhibits synergistic anti-HCC effect. Our data show that the combination treatment exhibits synergistic e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Minting, Wu, Hsin Ling, Wong, Tsz Sin, Chen, Baisen, Gong, Rui-Hong, Wong, Hoi Leong Xavier, Xiao, Haitao, Bian, Zhaoxiang, Kwan, Hiu Yee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131852/ https://www.ncbi.nlm.nih.gov/pubmed/34025421 http://dx.doi.org/10.3389/fphar.2021.657080

Ejemplares similares

Combination of artesunate and WNT974 induces KRAS protein degradation by upregulating E3 ligase ANACP2 and β-TrCP in the ubiquitin–proteasome pathway
por: Gong, Rui-Hong, et al.
Publicado: (2022)

Tumor necrosis factor receptor signaling is a driver of chronic lymphocytic leukemia that can be therapeutically targeted by the flavonoid wogonin
por: Dürr, Claudia, et al.
Publicado: (2018)

Baicalein is a novel TLR4‐targeting therapeutics agent that inhibits TLR4/HIF‐1α/VEGF signaling pathway in colorectal cancer
por: Chen, Minting, et al.
Publicado: (2021)

Nonhematopoietic cells selected for resistance to tumor necrosis factor produce tumor necrosis factor
Publicado: (1986)

Tumor Necrosis Factor and Splenectomy
por: Yavaşoğlu, İrfan
Publicado: (2016)

Tumor necrosis factor receptor I, II and tumor necrosis factor-α levels in patients with burns
por: Endo, S, et al.
Publicado: (2000)

Inflammation, tumor necrosis factor, and toxicology.
por: Luster, M I
Publicado: (1998)

Tumor Necrosis Factor and Regulatory T Cells
por: Jung, Min Kyung, et al.
Publicado: (2019)

Tumor necrosis factor polymorphisms associated with tumor necrosis factor production influence the risk of idiopathic intermediate uveitis
por: Atan, Denize, et al.
Publicado: (2013)

Novel strategies to mimic transmembrane tumor necrosis factor-dependent activation of tumor necrosis factor receptor 2
por: Fischer, Roman, et al.
Publicado: (2017)

In vivo Anti‐tumor Efficacy of Polyethylene Glycol‐modified Tumor Necrosis Factor‐α against Tumor Necrosis Factor‐resistant Tumors
por: Tsutsumi, Yasuo, et al.
Publicado: (1996)

Early effects of tumor necrosis factor inhibition on bone homeostasis after soluble tumor necrosis factor receptor use
por: Lim, Mie Jin, et al.
Publicado: (2014)

Small tumor necrosis factor receptor biologics inhibit the tumor necrosis factor-p38 signalling axis and inflammation
por: Mukaro, Violet R., et al.
Publicado: (2018)

Interference of tumor necrosis factor inhibitor treatments on soluble tumor necrosis factor receptor 2 levels in rheumatoid arthritis
por: Yang, Nicole, et al.
Publicado: (2019)

Role of the Interaction of Tumor Necrosis Factor-α and Tumor Necrosis Factor Receptors 1 and 2 in Bone-Related Cells
por: Kitaura, Hideki, et al.
Publicado: (2022)

RNPS1 inhibits excessive tumor necrosis factor/tumor necrosis factor receptor signaling to support hematopoiesis in mice
por: Zhong, Xue, et al.
Publicado: (2022)

Modulation of Tumor Necrosis Factor by Microbial Pathogens
por: Rahman, Masmudur M, et al.
Publicado: (2006)

Enhancement of experimental metastasis by tumor necrosis factor
Publicado: (1993)

Tumor necrosis factor: is it time to change the name?
por: Pisetsky, David S
Publicado: (2014)

Tumor necrosis factor inhibitors – state of knowledge
por: Lis, Krzysztof, et al.
Publicado: (2014)

Tumor Necrosis Factor Production and Colon Cancer
por: Ito, Hisashi, et al.
Publicado: (1996)

Listeria Cerebritis with Tumor Necrosis Factor Inhibition
por: Reilly, Eileen, et al.
Publicado: (2020)

Tumor necrosis factor as a pharmacological target
por: Ghezzi, Pietro, et al.
Publicado: (2005)

Tumor necrosis factor and interferon: cytokines in harmony
por: Bartee, Eric, et al.
Publicado: (2008)

Tumor Necrosis Factor Alpha Signaling and Organogenesis
por: You, Kai, et al.
Publicado: (2021)

Tumor Necrosis Factor: What Is in a Name?
por: Wang, Xinming, et al.
Publicado: (2022)

Transmembrane tumor necrosis factor alpha attenuates pressure-overload cardiac hypertrophy via tumor necrosis factor receptor 2
por: Miao, Kun, et al.
Publicado: (2020)

CD4(+) T-Cell Dysfunction in Severe COVID-19 Disease Is Tumor Necrosis Factor-α/Tumor Necrosis Factor Receptor 1–Dependent
por: Popescu, Iulia, et al.
Publicado: (2022)

Targeting tumor-necrosis factor receptor pathways for tumor immunotherapy
por: Schaer, David A, et al.
Publicado: (2014)

Effects of Tumor Necrosis Factor and Hyperthermia on Meth‐A Tumors
por: Hiraoka, Masahiro, et al.
Publicado: (1991)

Preventing synaptic deficits in Alzheimer’s disease by inhibiting tumor necrosis factor alpha signaling
por: Cavanagh, Chelsea, et al.
Publicado: (2018)

Mechanism of Synergistic Cytotoxic Effect between Tumor Necrosis Factor and Hyperthermia
por: Yamauchi, Naofumi, et al.
Publicado: (1992)

Glucocorticoid-mediated inhibition of endotoxin-induced intratumor tumor necrosis factor production and tumor hemorrhagic necrosis and regression
Publicado: (1989)

The p38 MAPK Inhibitor SB203580 Abrogates Tumor Necrosis Factor-Induced Proliferative Expansion of Mouse CD4(+)Foxp3(+) Regulatory T Cells
por: He, Tianzhen, et al.
Publicado: (2018)

Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-α
por: Robertson, Janice, et al.
Publicado: (2001)

Tumor necrosis factor receptor-mediated signaling pathways
Publicado: (1994)

Fibrinolytic response to tumor necrosis factor in healthy subjects
Publicado: (1991)

Tumor necrosis factor identified in multiple sclerosis brain
Publicado: (1989)

A human inhibitor of tumor necrosis factor alpha
Publicado: (1988)

Influence of tumor necrosis factor α in rheumatoid arthritis
por: Kulp, Werner, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_um4qi23uf1l73usdnjs83ur6i3