P2x7 Receptor Signaling Blockade Reduces Lung Inflammation and Necrosis During Severe Experimental Tuberculosis

The risk of developing severe forms of tuberculosis has increased by the acquired immunodeficiency syndrome (AIDS) epidemic, lack of effective drugs to eliminate latent infection and the emergence of drug-resistant mycobacterial strains. Excessive inflammatory response and tissue damage associated w...

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Detalles Bibliográficos
Autores principales: Santiago-Carvalho, Igor, de Almeida-Santos, Gislane, Bomfim, Caio César Barbosa, de Souza, Paula Carolina, Silva, Juan Carlo Santos e, de Melo, Bruno Marcel Silva, Amaral, Eduardo Pinheiro, Cione, Marcos Vinícios Pinheiro, Lasunskaia, Elena, Hirata, Mario Hiroyuki, Alves-Filho, José Carlos Farias, Nakaya, Helder Imoto, Alvarez, José Maria, D’Império Lima, Maria Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131868/
https://www.ncbi.nlm.nih.gov/pubmed/34026666
http://dx.doi.org/10.3389/fcimb.2021.672472

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