Safety and tolerability of liquid amikacin in antibiotic-loaded bone cement – a case series

High-dose liquid antibiotics are uncommon in bone cement. We present a case series of patients in which up to 16 mL of liquid amikacin (250 mg mL [Formula: see text]) was successfully incorporated into bone cement to treat periprosthetic joint infections. We did not observe adverse drug reactions de...

Descripción completa

Detalles Bibliográficos
Autores principales: Tai, Don Bambino Geno, Brinkman, Nathan J., Abu Saleh, Omar, Osmon, Douglas R., Abdel, Matthew P., Rivera, Christina G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Copernicus GmbH 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131961/
https://www.ncbi.nlm.nih.gov/pubmed/34084704
http://dx.doi.org/10.5194/jbji-6-147-2021
Descripción
Sumario:High-dose liquid antibiotics are uncommon in bone cement. We present a case series of patients in which up to 16 mL of liquid amikacin (250 mg mL [Formula: see text]) was successfully incorporated into bone cement to treat periprosthetic joint infections. We did not observe adverse drug reactions definitively attributed to its use.

Ejemplares similares