Safety and tolerability of liquid amikacin in antibiotic-loaded bone cement – a case series

High-dose liquid antibiotics are uncommon in bone cement. We present a case series of patients in which up to 16 mL of liquid amikacin (250 mg mL [Formula: see text]) was successfully incorporated into bone cement to treat periprosthetic joint infections. We did not observe adverse drug reactions de...

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Detalles Bibliográficos
Autores principales: Tai, Don Bambino Geno, Brinkman, Nathan J., Abu Saleh, Omar, Osmon, Douglas R., Abdel, Matthew P., Rivera, Christina G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Copernicus GmbH 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131961/
https://www.ncbi.nlm.nih.gov/pubmed/34084704
http://dx.doi.org/10.5194/jbji-6-147-2021
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author Tai, Don Bambino Geno
Brinkman, Nathan J.
Abu Saleh, Omar
Osmon, Douglas R.
Abdel, Matthew P.
Rivera, Christina G.
author_facet Tai, Don Bambino Geno
Brinkman, Nathan J.
Abu Saleh, Omar
Osmon, Douglas R.
Abdel, Matthew P.
Rivera, Christina G.
author_sort Tai, Don Bambino Geno
collection PubMed
description High-dose liquid antibiotics are uncommon in bone cement. We present a case series of patients in which up to 16 mL of liquid amikacin (250 mg mL [Formula: see text]) was successfully incorporated into bone cement to treat periprosthetic joint infections. We did not observe adverse drug reactions definitively attributed to its use.
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spelling pubmed-81319612021-06-02 Safety and tolerability of liquid amikacin in antibiotic-loaded bone cement – a case series Tai, Don Bambino Geno Brinkman, Nathan J. Abu Saleh, Omar Osmon, Douglas R. Abdel, Matthew P. Rivera, Christina G. J Bone Jt Infect Brief Report High-dose liquid antibiotics are uncommon in bone cement. We present a case series of patients in which up to 16 mL of liquid amikacin (250 mg mL [Formula: see text]) was successfully incorporated into bone cement to treat periprosthetic joint infections. We did not observe adverse drug reactions definitively attributed to its use. Copernicus GmbH 2021-04-26 /pmc/articles/PMC8131961/ /pubmed/34084704 http://dx.doi.org/10.5194/jbji-6-147-2021 Text en Copyright: © 2021 Don Bambino Geno Tai et al. https://creativecommons.org/licenses/by/4.0/ This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/
spellingShingle Brief Report
Tai, Don Bambino Geno
Brinkman, Nathan J.
Abu Saleh, Omar
Osmon, Douglas R.
Abdel, Matthew P.
Rivera, Christina G.
Safety and tolerability of liquid amikacin in antibiotic-loaded bone cement – a case series
title Safety and tolerability of liquid amikacin in antibiotic-loaded bone cement – a case series
title_full Safety and tolerability of liquid amikacin in antibiotic-loaded bone cement – a case series
title_fullStr Safety and tolerability of liquid amikacin in antibiotic-loaded bone cement – a case series
title_full_unstemmed Safety and tolerability of liquid amikacin in antibiotic-loaded bone cement – a case series
title_short Safety and tolerability of liquid amikacin in antibiotic-loaded bone cement – a case series
title_sort safety and tolerability of liquid amikacin in antibiotic-loaded bone cement – a case series
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131961/
https://www.ncbi.nlm.nih.gov/pubmed/34084704
http://dx.doi.org/10.5194/jbji-6-147-2021
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