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Cryptococcus meningitis presented with multiple cerebral infarcts in an immunocompetent patient

Cryptococcus neoformans is generally observed with immunosuppressive conditions. Rarely, it may be seen in immunocompetent individuals and presented with non-specific conditions. We described an immunocompetent case of cryptococcal meningitis presented with multiple cerebral infarcts. Despite the la...

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Detalles Bibliográficos
Autores principales: Erturk Sengel, Buket, Tukenmez Tigen, Elif, Can Sarinoglu, Rabia, Midi, Ipek, Cerikcioglu, Nilgun, Odabasi, Zekaver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8131984/
https://www.ncbi.nlm.nih.gov/pubmed/34026541
http://dx.doi.org/10.1016/j.idcr.2021.e01154
Descripción
Sumario:Cryptococcus neoformans is generally observed with immunosuppressive conditions. Rarely, it may be seen in immunocompetent individuals and presented with non-specific conditions. We described an immunocompetent case of cryptococcal meningitis presented with multiple cerebral infarcts. Despite the late diagnosis and emergence of hydrocephalus during treatment, the patient was recovered without any sequelae. In immunocompetent patients, the conventional diagnostics tests may be negative because of the low fungal load. If it is available, the Biofire FilmArray meningitis panel has high sensitivity and specificity for diagnosis.