Engineered Matrices Enable the Culture of Human Patient‐Derived Intestinal Organoids

Human intestinal organoids from primary human tissues have the potential to revolutionize personalized medicine and preclinical gastrointestinal disease models. A tunable, fully defined, designer matrix, termed hyaluronan elastin‐like protein (HELP) is reported, which enables the formation, differen...

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Detalles Bibliográficos
Autores principales: Hunt, Daniel R., Klett, Katarina C., Mascharak, Shamik, Wang, Huiyuan, Gong, Diana, Lou, Junzhe, Li, Xingnan, Cai, Pamela C., Suhar, Riley A., Co, Julia Y., LeSavage, Bauer L., Foster, Abbygail A., Guan, Yuan, Amieva, Manuel R., Peltz, Gary, Xia, Yan, Kuo, Calvin J., Heilshorn, Sarah C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132048/
https://www.ncbi.nlm.nih.gov/pubmed/34026461
http://dx.doi.org/10.1002/advs.202004705

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