Cargando…

CUL4B Promotes Breast Carcinogenesis by Coordinating with Transcriptional Repressor Complexes in Response to Hypoxia Signaling Pathway

Cullin4B (CUL4B) is a scaffold protein of the CUL4B‐Ring E3 ligase (CRL4B) complex. However, the role of CUL4B in the development of breast cancer remains poorly understood. Here it is shown that CRL4B interacts with multiple histone deacetylase (HDAC)‐containing corepressor complexes, including MTA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Wei, Zhang, Jingyao, Huo, Miaomiao, Gao, Jie, Yang, Tianshu, Yin, Xin, Wang, Pei, Leng, Shuai, Feng, Dandan, Chen, Yang, Yang, Yang, Wang, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132058/ https://www.ncbi.nlm.nih.gov/pubmed/34026424 http://dx.doi.org/10.1002/advs.202001515

Ejemplares similares

SIRT1 coordinates with the CRL4B complex to regulate pancreatic cancer stem cells to promote tumorigenesis
por: Leng, Shuai, et al.
Publicado: (2021)

Snail/PRMT5/NuRD complex contributes to DNA hypermethylation in cervical cancer by TET1 inhibition
por: Gao, Jie, et al.
Publicado: (2021)

REST is a hypoxia-responsive transcriptional repressor
por: Cavadas, Miguel A. S., et al.
Publicado: (2016)

HIF repressors under chronic hypoxia
por: Luo, Weibo, et al.
Publicado: (2016)

The histone deacetylase inhibitor PCI-24781 impairs calcium influx and inhibits proliferation and metastasis in breast cancer
por: Yang, Tianshu, et al.
Publicado: (2021)

Structure‐Enabled Discovery of a Stapled Peptide Inhibitor to Target the Oncogenic Transcriptional Repressor TLE1
por: McGrath, Sally, et al.
Publicado: (2017)

CUL2 overexpression driven by CUL2/E2F1/miR-424 regulatory loop promotes HPV16 E7 induced cervical carcinogenesis
por: Xu, Junfen, et al.
Publicado: (2016)

RUNX2 recruits the NuRD(MTA1)/CRL4B complex to promote breast cancer progression and bone metastasis
por: Yin, Xin, et al.
Publicado: (2022)

The Homeotic Protein SIX3 Suppresses Carcinogenesis and Metastasis through Recruiting the LSD1/NuRD(MTA3) Complex
por: Zheng, Yu, et al.
Publicado: (2018)

PHF20L1 as a H3K27me2 reader coordinates with transcriptional repressors to promote breast tumorigenesis
por: Hou, Yongqiang, et al.
Publicado: (2020)

A genetic biosensor for identification of transcriptional repressors of target promoters
por: Wang, Weishan, et al.
Publicado: (2015)

Gossypol inhibits cullin neddylation by targeting SAG-CUL5 and RBX1-CUL1 complexes
por: Yu, Qing, et al.
Publicado: (2020)

NIR responsive nanoenzymes via photothermal ablation and hypoxia reversal to potentiate the STING-dependent innate antitumor immunity
por: Li, Qianzhe, et al.
Publicado: (2023)

JFK Is a Hypoxia-Inducible Gene That Functions to Promote Breast Carcinogenesis
por: Yang, Ziran, et al.
Publicado: (2021)

Comprehensively prognostic and immunological analysis of snail family transcriptional repressor 2 in pan-cancer and identification in pancreatic carcinoma
por: Zhang, Dandan, et al.
Publicado: (2023)

A Phosphorescent Iridium(III) Complex‐Modified Nanoprobe for Hypoxia Bioimaging Via Time‐Resolved Luminescence Microscopy
por: Lv, Wen, et al.
Publicado: (2015)

Cul-de-sac : roman /
por: Thériault, Yves
Publicado: (1981)

TGF-β Repressors SnoN and Ski Are Implicated in Human Colorectal Carcinogenesis
por: Bravou, Vasiliki, et al.
Publicado: (2009)

The Proto-Oncogene Int6 Is Essential for Neddylation of Cul1 and Cul3 in Drosophila
por: Rencus-Lazar, Sigal, et al.
Publicado: (2008)

Current trends of high-risk gene Cul3 in neurodevelopmental disorders
por: Lin, Ping, et al.
Publicado: (2023)

Multifunctional Phosphorescent Conjugated Polymer Dots for Hypoxia Imaging and Photodynamic Therapy of Cancer Cells
por: Zhou, Xiaobo, et al.
Publicado: (2015)

Cul4B is a novel prognostic marker in cholangiocarcinoma
por: Li, Pengyu, et al.
Publicado: (2017)

Coordinated epigenetic remodelling of transcriptional networks occurs during early breast carcinogenesis
por: Locke, Warwick J, et al.
Publicado: (2015)

Arabidopsis FLC clade members form flowering-repressor complexes coordinating responses to endogenous and environmental cues
por: Gu, Xiaofeng, et al.
Publicado: (2013)

Cul4A is an oncogene in malignant pleural mesothelioma
por: Hung, Ming-Szu, et al.
Publicado: (2011)

Inhibitory effect of CUL1 on atherosclerosis through the p53 pathway
por: Zhang, Xi, et al.
Publicado: (2022)

MicroRNA-154-5p regulates the HPV16 E7-pRb pathway in Cervical Carcinogenesis by targeting CUL2
por: Zhao, Weihong, et al.
Publicado: (2020)

Carcinogenesis promotion in oral squamous cell carcinoma: KDM4A complex-mediated gene transcriptional suppression by LEF1
por: Hou, Yiming, et al.
Publicado: (2023)

The PRMT6/PARP1/CRL4B Complex Regulates the Circadian Clock and Promotes Breast Tumorigenesis
por: Yang, Tianshu, et al.
Publicado: (2023)

Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex
por: Nangle, Shannon N, et al.
Publicado: (2014)

AITRL, an evolutionarily conserved plant specific transcription repressor regulates ABA response in Arabidopsis
por: Ma, Yanxing, et al.
Publicado: (2021)

Transcriptional Repressor NIR Functions in the Ribosome RNA Processing of Both 40S and 60S Subunits
por: Wu, Jianguo, et al.
Publicado: (2012)

Glycine decarboxylase is a target for transcriptional repressor Snail
por: Chen, Guohua, et al.
Publicado: (2014)

JARID2 coordinates with the NuRD complex to facilitate breast tumorigenesis through response to adipocyte‐derived leptin
por: Liu, Wei, et al.
Publicado: (2023)

ACLY ubiquitination by CUL3-KLHL25 induces the reprogramming of fatty acid metabolism to facilitate iTreg differentiation
por: Tian, Miaomiao, et al.
Publicado: (2021)

Hypoxia and Angiogenesis in Endometrioid Endometrial Carcinogenesis
por: Horrée, Nicole, et al.
Publicado: (2007)

The Coordinated Action of MYB Activators and Repressors Controls Proanthocyanidin and Anthocyanin Biosynthesis in Vaccinium
por: Lafferty, Declan J., et al.
Publicado: (2022)

CUL4B facilitates HBV replication by promoting HBx stabilization
por: Shan, Haixia, et al.
Publicado: (2022)

PEAPOD repressors modulate and coordinate developmental responses to light intensity in Arabidopsis
por: White, Derek W. R.
Publicado: (2022)

A Multimaterial Scaffold With Tunable Properties: Toward Bone Tissue Repair
por: Feng, Pei, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_mjjtrbe4iq4htq348pbrfrd819