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Association of Socioeconomic Status With Dementia Diagnosis Among Older Adults in Denmark

IMPORTANCE: Low socioeconomic status (SES) has been identified as a risk factor for the development of dementia. However, few studies have focused on the association between SES and dementia diagnostic evaluation on a population level. OBJECTIVE: To investigate whether household income (HHI) is asso...

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Autores principales: Petersen, Jindong Ding, Wehberg, Sonja, Packness, Aake, Svensson, Nanna Herning, Hyldig, Nana, Raunsgaard, Søren, Andersen, Merethe Kirstine, Ryg, Jesper, Mercer, Stewart W., Søndergaard, Jens, Waldorff, Frans Boch
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132141/
https://www.ncbi.nlm.nih.gov/pubmed/34003271
http://dx.doi.org/10.1001/jamanetworkopen.2021.10432
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author Petersen, Jindong Ding
Wehberg, Sonja
Packness, Aake
Svensson, Nanna Herning
Hyldig, Nana
Raunsgaard, Søren
Andersen, Merethe Kirstine
Ryg, Jesper
Mercer, Stewart W.
Søndergaard, Jens
Waldorff, Frans Boch
author_facet Petersen, Jindong Ding
Wehberg, Sonja
Packness, Aake
Svensson, Nanna Herning
Hyldig, Nana
Raunsgaard, Søren
Andersen, Merethe Kirstine
Ryg, Jesper
Mercer, Stewart W.
Søndergaard, Jens
Waldorff, Frans Boch
author_sort Petersen, Jindong Ding
collection PubMed
description IMPORTANCE: Low socioeconomic status (SES) has been identified as a risk factor for the development of dementia. However, few studies have focused on the association between SES and dementia diagnostic evaluation on a population level. OBJECTIVE: To investigate whether household income (HHI) is associated with dementia diagnosis and cognitive severity at the time of diagnosis. DESIGN, SETTING, AND PARTICIPANTS: This population- and register-based cross-sectional study analyzed health, social, and economic data obtained from various Danish national registers. The study population comprised individuals who received a first-time referral for a diagnostic evaluation for dementia to the secondary health care sector of Denmark between January 1, 2017, and December 17, 2018. Dementia-related health data were retrieved from the Danish Quality Database for Dementia. Data analysis was conducted from October 2019 to December 2020. EXPOSURES: Annual HHI (used as a proxy for SES) for 2015 and 2016 was obtained from Statistics Denmark and categorized into upper, middle, and lower tertiles within 5-year interval age groups. MAIN OUTCOMES AND MEASURES: Dementia diagnoses (Alzheimer disease, vascular dementia, mixed dementia, dementia with Lewy bodies, Parkinson disease dementia, or other) and cognitive stages at diagnosis (cognitively intact; mild cognitive impairment but not dementia; or mild, moderate, or severe dementia) were retrieved from the database. Univariable and multivariable logistic and linear regressions adjusted for age group, sex, region of residence, household type, period (2017 and 2018), medication type, and medical conditions were analyzed for a possible association between HHI and receipt of dementia diagnosis. RESULTS: Among the 10 191 individuals (mean [SD] age, 75 [10] years; 5476 women [53.7%]) included in the study, 8844 (86.8%) were diagnosed with dementia. Individuals with HHI in the upper tertile compared with those with lower-tertile HHI were less likely to receive a dementia diagnosis after referral (odds ratio, 0.65; 95% CI, 0.55-0.78) and, if diagnosed with dementia, had less severe cognitive stage (β, −0.16; 95% CI, −0.21 to −0.10). Individuals with middle-tertile HHI did not significantly differ from those with lower-tertile HHI in terms of dementia diagnosis (odds ratio, 0.92; 95% CI, 0.77-1.09) and cognitive stage at diagnosis (β, 0.01; 95% CI, −0.04 to 0.06). CONCLUSIONS AND RELEVANCE: The results of this study revealed a social inequality in dementia diagnostic evaluation: in Denmark, people with higher income seem to receive an earlier diagnosis. Public health strategies should target people with lower SES for earlier dementia detection and intervention.
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spelling pubmed-81321412021-05-24 Association of Socioeconomic Status With Dementia Diagnosis Among Older Adults in Denmark Petersen, Jindong Ding Wehberg, Sonja Packness, Aake Svensson, Nanna Herning Hyldig, Nana Raunsgaard, Søren Andersen, Merethe Kirstine Ryg, Jesper Mercer, Stewart W. Søndergaard, Jens Waldorff, Frans Boch JAMA Netw Open Original Investigation IMPORTANCE: Low socioeconomic status (SES) has been identified as a risk factor for the development of dementia. However, few studies have focused on the association between SES and dementia diagnostic evaluation on a population level. OBJECTIVE: To investigate whether household income (HHI) is associated with dementia diagnosis and cognitive severity at the time of diagnosis. DESIGN, SETTING, AND PARTICIPANTS: This population- and register-based cross-sectional study analyzed health, social, and economic data obtained from various Danish national registers. The study population comprised individuals who received a first-time referral for a diagnostic evaluation for dementia to the secondary health care sector of Denmark between January 1, 2017, and December 17, 2018. Dementia-related health data were retrieved from the Danish Quality Database for Dementia. Data analysis was conducted from October 2019 to December 2020. EXPOSURES: Annual HHI (used as a proxy for SES) for 2015 and 2016 was obtained from Statistics Denmark and categorized into upper, middle, and lower tertiles within 5-year interval age groups. MAIN OUTCOMES AND MEASURES: Dementia diagnoses (Alzheimer disease, vascular dementia, mixed dementia, dementia with Lewy bodies, Parkinson disease dementia, or other) and cognitive stages at diagnosis (cognitively intact; mild cognitive impairment but not dementia; or mild, moderate, or severe dementia) were retrieved from the database. Univariable and multivariable logistic and linear regressions adjusted for age group, sex, region of residence, household type, period (2017 and 2018), medication type, and medical conditions were analyzed for a possible association between HHI and receipt of dementia diagnosis. RESULTS: Among the 10 191 individuals (mean [SD] age, 75 [10] years; 5476 women [53.7%]) included in the study, 8844 (86.8%) were diagnosed with dementia. Individuals with HHI in the upper tertile compared with those with lower-tertile HHI were less likely to receive a dementia diagnosis after referral (odds ratio, 0.65; 95% CI, 0.55-0.78) and, if diagnosed with dementia, had less severe cognitive stage (β, −0.16; 95% CI, −0.21 to −0.10). Individuals with middle-tertile HHI did not significantly differ from those with lower-tertile HHI in terms of dementia diagnosis (odds ratio, 0.92; 95% CI, 0.77-1.09) and cognitive stage at diagnosis (β, 0.01; 95% CI, −0.04 to 0.06). CONCLUSIONS AND RELEVANCE: The results of this study revealed a social inequality in dementia diagnostic evaluation: in Denmark, people with higher income seem to receive an earlier diagnosis. Public health strategies should target people with lower SES for earlier dementia detection and intervention. American Medical Association 2021-05-18 /pmc/articles/PMC8132141/ /pubmed/34003271 http://dx.doi.org/10.1001/jamanetworkopen.2021.10432 Text en Copyright 2021 Petersen JD et al. JAMA Network Open. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the CC-BY License.
spellingShingle Original Investigation
Petersen, Jindong Ding
Wehberg, Sonja
Packness, Aake
Svensson, Nanna Herning
Hyldig, Nana
Raunsgaard, Søren
Andersen, Merethe Kirstine
Ryg, Jesper
Mercer, Stewart W.
Søndergaard, Jens
Waldorff, Frans Boch
Association of Socioeconomic Status With Dementia Diagnosis Among Older Adults in Denmark
title Association of Socioeconomic Status With Dementia Diagnosis Among Older Adults in Denmark
title_full Association of Socioeconomic Status With Dementia Diagnosis Among Older Adults in Denmark
title_fullStr Association of Socioeconomic Status With Dementia Diagnosis Among Older Adults in Denmark
title_full_unstemmed Association of Socioeconomic Status With Dementia Diagnosis Among Older Adults in Denmark
title_short Association of Socioeconomic Status With Dementia Diagnosis Among Older Adults in Denmark
title_sort association of socioeconomic status with dementia diagnosis among older adults in denmark
topic Original Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132141/
https://www.ncbi.nlm.nih.gov/pubmed/34003271
http://dx.doi.org/10.1001/jamanetworkopen.2021.10432
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