Cargando…

The Hantzsch reaction for nitrogen-13 PET: preparation of [(13)N]nifedipine and derivatives

Nitrogen-13 is an attractive but under-used PET radionuclide for labelling molecules of biological and pharmaceutical interest, complementing other PET radionuclides. Its short half-life (t(1/2) = 9.97 min) imposes synthetic challenges, but we have expanded the hitherto limited pool of (13)N labelli...

Descripción completa

Detalles Bibliográficos
Autores principales:	Blower, Julia E., Ma, Michelle T., Al-Salemee, Fahad A. I., Gee, Antony D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132178/ https://www.ncbi.nlm.nih.gov/pubmed/33876157 http://dx.doi.org/10.1039/d1cc00495f

Ejemplares similares

Convergent synthesis of (13)N-labelled Peptidic structures using aqueous [(13)N]NH(3)
por: Blower, Julia E., et al.
Publicado: (2017)

Accelerated Hantzsch electrospray synthesis with temporal control of reaction intermediates
por: Bain, Ryan M., et al.
Publicado: (2015)

Non-invasive radionuclide imaging of trace metal trafficking in health and disease: “PET metallomics”
por: Firth, George, et al.
Publicado: (2022)

Evaluation of the antioxidant activities of fatty polyhydroquinolines synthesized by Hantzsch multicomponent reactions
por: Brinkerhoff, Rafael Centuriao, et al.
Publicado: (2019)

Application of Hantzsch reaction for sensitive determination of eflornithine in cream, plasma and urine samples
por: Almahri, Albandary, et al.
Publicado: (2021)

Green approach for synthesis of bioactive Hantzsch 1,4-dihydropyridine derivatives based on thiophene moiety via multicomponent reaction
por: Sharma, M. G., et al.
Publicado: (2017)

Electron paramagnetic resonance spectroscopic studies of the electron transfer reaction of Hantzsch ester and a pyrylium salt
por: Sebők-Nagy, K., et al.
Publicado: (2018)

High-Throughput Preparation of Antibacterial Polymers from Natural Product Derivatives via the Hantzsch Reaction
por: Liu, Guoqiang, et al.
Publicado: (2019)

Derivative Matrix-Isopotential Synchronous Spectrofluorimetry and Hantzsch Reaction: A Direct Route to Simultaneous Determination of Urinary δ-Aminolevulinic Acid and Porphobilinogen
por: Ajmal, Muhammad, et al.
Publicado: (2022)

Theoretical investigation on the nature of 4-substituted Hantzsch esters as alkylation agents
por: Shen, Guang-Bin, et al.
Publicado: (2020)

High-throughput preparation of radioprotective polymers via Hantzsch’s reaction for in vivo X-ray damage determination
por: Liu, Guoqiang, et al.
Publicado: (2020)

In Vivo Trafficking of the Anticancer Drug Tris(8-Quinolinolato) Gallium (III) (KP46) by Gallium-68/67 PET/SPECT Imaging
por: Darwesh, Afnan M. F., et al.
Publicado: (2023)

Catalyst-Free Synthesis of Polysubstituted 5-Acylamino-1,3-Thiazoles via Hantzsch Cyclization of α-Chloroglycinates
por: Tomassetti, Mara, et al.
Publicado: (2019)

A novel AIE-active dye for fluorescent nanoparticles by one-pot combination of Hantzsch reaction and RAFT polymerization: synthesis, molecular structure and application in cell imaging
por: Chen, Yali, et al.
Publicado: (2019)

One-step, kit-based radiopharmaceuticals for molecular SPECT imaging: a versatile diphosphine chelator for (99m)Tc radiolabelling of peptides
por: Hungnes, Ingebjørg N., et al.
Publicado: (2021)

(15)N labeling and analysis of (13)C–(15)N and (1)H–(15)N couplings in studies of the structures and chemical transformations of nitrogen heterocycles
por: Deev, Sergey L., et al.
Publicado: (2019)

Mechanistic insight into the catalytic hydrogenation of nonactivated aldehydes with a Hantzsch ester in the presence of a series of organoboranes: NMR and DFT studies
por: Hamasaka, Go, et al.
Publicado: (2019)

Retraction: One-pot synthesis of Hantzsch dihydropyridines using a highly efficient and stable PdRuNi@GO catalyst
por: Fisher, Laura
Publicado: (2021)

A Theoretical Study on the Structural, Electronic, and Magnetic Properties of Bimetallic Pt(13−n)Ni(n) (N = 0, 3, 6, 9, 13) Nanoclusters to Unveil the Catalytic Mechanisms for the Water-Gas Shift Reaction
por: Barrionuevo, Manoel Victor Frutuoso, et al.
Publicado: (2022)

Effect of (H(2)O)(n) (n = 0–3, 13) on the NH(3) + OH reaction in the gas and liquid phases
por: Zhou, Yujie, et al.
Publicado: (2022)

“On-Water” Catalyst-Free Ecofriendly Synthesis of the Hantzsch Dihydropyridines
por: Pramanik, Amit, et al.
Publicado: (2012)

Copper-catalyzed [1,3]-nitrogen rearrangement of O-aryl ketoximes via oxidative addition of N–O bond in inverse electron flow
por: Suzuki, Mao, et al.
Publicado: (2023)

Facilitated inversion complicates the stereodynamics of an S(N)2 reaction at nitrogen center
por: Papp, Dóra, et al.
Publicado: (2021)

One-step preparation of novel 1-(N-indolyl)-1,3-butadienes by base-catalysed isomerization of alkynes as an access to 5-(N-indolyl)-naphthoquinones
por: Pis Diez, C. M., et al.
Publicado: (2018)

Human (13)N-ammonia PET studies: the importance of measuring (13)N-ammonia metabolites in blood
por: Keiding, Susanne, et al.
Publicado: (2010)

3-Aminooxetanes: versatile 1,3-amphoteric molecules for intermolecular annulation reactions
por: Lai, Zengwei, et al.
Publicado: (2020)

Asymmetric ring-opening reactions of donor–acceptor cyclopropanes with 1,3-cyclodiones
por: Zhang, Dongxin, et al.
Publicado: (2023)

FeNH(4)(SO(4))(2)·12H(2)O (alum)-catalyzed preparation of 1,4-dihydropyridines: improved conditions for the Hantzsch reaction
por: Mohammadi, Ali A., et al.
Publicado: (2011)

Three-component reaction of azulene, aryl glyoxal and 1,3-dicarbonyl compound for the synthesis of various azulene derivatives
por: Gong, Jing, et al.
Publicado: (2020)

Thioether-functionalized trifluoromethyl-alkynes, 1,3-dienes and allenes: divergent synthesis from reaction of 2-trifluoromethyl-1,3-conjugated enynes with sulfur nucleophiles
por: Cheng, Huayu, et al.
Publicado: (2018)

Electronic synergism of pyridinic- and graphitic-nitrogen on N-doped carbons for the oxygen reduction reaction
por: Ning, Xiaomei, et al.
Publicado: (2018)

Revisiting the nature of Cu sites in the activated Cu-SSZ-13 catalyst for SCR reaction
por: Borfecchia, E., et al.
Publicado: (2015)

Photochemical halogen-bonding assisted carbothiophosphorylation reactions of alkenyl and 1,3-dienyl bromides
por: Piedra, Helena F., et al.
Publicado: (2023)

Manipulating the In Vivo Behaviour of (68)Ga with Tris(Hydroxypyridinone) Chelators: Pretargeting and Blood Clearance
por: Imberti, Cinzia, et al.
Publicado: (2020)

A computational study to determine whether substituents make E(13)[triple bond, length as m-dash]nitrogen (E(13) = B, Al, Ga, In, and Tl) triple bonds synthetically accessible
por: Zhang, Shi-Lin, et al.
Publicado: (2019)

New multicomponent reactions in water: a facile synthesis of 1,3-dioxo-2-indanilidene-heterocyclic scaffolds and indenoquinoxalines through reaction of ninhydrin-malononitrile adduct with diverse N-binucleophiles
por: Rahimi, Zahra, et al.
Publicado: (2022)

Green Approach—Multicomponent Production of Boron—Containing Hantzsch and Biginelli Esters
por: Martínez, Joel, et al.
Publicado: (2013)

Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives
por: Pachón Angona, Irene, et al.
Publicado: (2020)

Microporous hierarchically Zn-MOF as an efficient catalyst for the Hantzsch synthesis of polyhydroquinolines
por: Ramish, Sayed Mohammad, et al.
Publicado: (2022)

Mechanoenzymatic reactions for the hydrolysis of PET
por: Ambrose-Dempster, Esther, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_kse3afn1ndrjhfr1sb6b8dui5q