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The therapeutic effect of TBK1 in intervertebral disc degeneration via coordinating selective autophagy and autophagic functions

INTRODUCTION: While its innate immune function has been known, recent works of literature have focused on the role of Tank binding kinase 1 (TBK1) in regulating autophagy and it is unknown whether TBK1 protects against intervertebral disc degeneration (IVDD) through affecting autophagy. OBJECTIVES:...

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Detalles Bibliográficos
Autores principales:	Hu, Sunli, Chen, Liang, Al Mamun, Abdullah, Ni, Libin, Gao, Weiyang, Lin, Yan, Jin, Haiming, Zhang, Xiaolei, Wang, Xiangyang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Basic and Biological Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132185/ https://www.ncbi.nlm.nih.gov/pubmed/34026282 http://dx.doi.org/10.1016/j.jare.2020.08.011

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