Cargando…

Dynamic Interactions of Fully Glycosylated SARS-CoV-2 Spike Protein with Various Antibodies

The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents a public health crisis, and the vaccines that can induce highly potent neutralizing antibodies are essential for ending the pandemic. The spike (S) protein on the viral envelope mediates human angiotensin-converting...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cao, Yiwei, Choi, Yeol Kyo, Frank, Martin, Woo, Hyeonuk, Park, Sang-Jun, Yeom, Min Sun, Seok, Chaok, Im, Wonpil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132224/ https://www.ncbi.nlm.nih.gov/pubmed/34013268 http://dx.doi.org/10.1101/2021.05.10.443519

Ejemplares similares

Structure, Dynamics, Receptor Binding, and Antibody Binding of the Fully Glycosylated Full-Length SARS-CoV-2 Spike Protein in a Viral Membrane
por: Choi, Yeol Kyo, et al.
Publicado: (2021)

Developing a Fully Glycosylated Full-Length SARS-CoV-2 Spike Protein Model in a Viral Membrane
por: Woo, Hyeonuk, et al.
Publicado: (2020)

Developing a Fully-glycosylated Full-length SARS-CoV-2 Spike Protein Model in a Viral Membrane
por: Woo, Hyeonuk, et al.
Publicado: (2020)

Author Correction: Structural basis of neuropeptide Y signaling through Y1 receptor
por: Park, Chaehee, et al.
Publicado: (2022)

Structural basis of neuropeptide Y signaling through Y1 receptor
por: Park, Chaehee, et al.
Publicado: (2022)

Differential Interactions Between Human ACE2 and Spike RBD of SARS-CoV-2 Variants of Concern
por: Kim, Seonghan, et al.
Publicado: (2021)

Differential interactions between human ACE2 and spike RBD of SARS-CoV-2 variants of concern
por: Kim, Seonghan, et al.
Publicado: (2022)

Biomechanical characterization of SARS-CoV-2 spike RBD and human ACE2 protein-protein interaction
por: Cao, Wenpeng, et al.
Publicado: (2021)

CHARMM-GUI Membrane Builder: Past, Current, and Future Developments and Applications
por: Feng, Shasha, et al.
Publicado: (2023)

Binding of Human ACE2 and RBD of Omicron Enhanced by Unique Interaction Patterns Among SARS-CoV-2 Variants of Concern
por: Kim, Seonghan, et al.
Publicado: (2022)

CHARMM-GUI Multicomponent Assembler for Modeling and Simulation of Complex Multicomponent Systems
por: Kern, Nathan R., et al.
Publicado: (2023)

Evaluating GPCR modeling and docking strategies in the era of deep learning-based protein structure prediction
por: Lee, Sumin, et al.
Publicado: (2022)

CHARMM-GUI Membrane Builder for Lipid Nanoparticles with Ionizable Cationic Lipids and PEGylated Lipids
por: Park, Soohyung, et al.
Publicado: (2021)

Effects of N-glycosylation on protein conformation and dynamics: Protein Data Bank analysis and molecular dynamics simulation study
por: Lee, Hui Sun, et al.
Publicado: (2015)

O-Glycosylation Landscapes of SARS-CoV-2 Spike Proteins
por: Zhang, Yong, et al.
Publicado: (2021)

Expression, Glycosylation, and Modification of the Spike (S) Glycoprotein of SARS CoV
por: Shen, Shuo, et al.
Publicado: (2007)

A urine-based ELISA with recombinant non-glycosylated SARS-CoV-2 spike protein for detecting anti-SARS-CoV-2 spike antibodies
por: Ramos, Fernanda F., et al.
Publicado: (2023)

Development and simulation of fully glycosylated molecular models of ACE2-Fc fusion proteins and their interaction with the SARS-CoV-2 spike protein binding domain
por: Bernardi, Austen, et al.
Publicado: (2020)

Site-Specific Steric Control of SARS-CoV-2 Spike Glycosylation
por: Allen, Joel D., et al.
Publicado: (2021)

Effects of N-Glycan Composition on Structure and Dynamics of IgG1 Fc and Their Implications for Antibody Engineering
por: Lee, Hui Sun, et al.
Publicado: (2017)

Furin cleavage of the SARS-CoV-2 spike is modulated by O-glycosylation
por: Zhang, Liping, et al.
Publicado: (2021)

Furin cleavage of the SARS-CoV-2 spike is modulated by O-glycosylation
por: Zhang, Liping, et al.
Publicado: (2021)

Characterization and immunogenicity of SARS-CoV-2 spike proteins with varied glycosylation
por: Deng, Tingting, et al.
Publicado: (2022)

SARS-CoV-2 spike glycosylation affects function and neutralization sensitivity
por: Zhang, Fengwen, et al.
Publicado: (2023)

Evolving spike-protein N-glycosylation in SARS-CoV-2 variants
por: Baboo, Sabyasachi, et al.
Publicado: (2023)

The Answer Lies in the Energy: How Simple Atomistic Molecular Dynamics Simulations May Hold the Key to Epitope Prediction on the Fully Glycosylated SARS-CoV-2 Spike Protein
por: Serapian, Stefano A., et al.
Publicado: (2020)

Multimerization- and glycosylation-dependent receptor binding of SARS-CoV-2 spike proteins
por: Bouwman, Kim M., et al.
Publicado: (2021)

Impact of Expressing Cells on Glycosylation and Glycan of the SARS-CoV-2 Spike Glycoprotein
por: Wang, Yan, et al.
Publicado: (2021)

Glycosylation is key for enhancing drug recognition into spike glycoprotein of SARS-CoV-2
por: Ropón-Palacios, Georcki, et al.
Publicado: (2022)

Glycosylation and S-palmitoylation regulate SARS-CoV-2 spike protein intracellular trafficking
por: Tien, Chih-Feng, et al.
Publicado: (2022)

Quantitative profiling of N-glycosylation of SARS-CoV-2 spike protein variants
por: Xie, Yongjing, et al.
Publicado: (2023)

Glycosylation and oligomerization of the spike protein of marburg virus
por: Feldmann, H., et al.
Publicado: (1991)

Analysis of glycosylation and disulfide bonding of wild-type SARS-CoV-2 spike glycoprotein
por: Zhang, Shijian, et al.
Publicado: (2021)

Glycosylation and Serological Reactivity of an Expression-enhanced SARS-CoV-2 Viral Spike Mimetic
por: Chawla, Himanshi, et al.
Publicado: (2022)

Dual nature of human ACE2 glycosylation in binding to SARS-CoV-2 spike
por: Mehdipour, Ahmad Reza, et al.
Publicado: (2021)

Suppression of O-Linked Glycosylation of the SARS-CoV-2 Spike by Quaternary Structural Restraints
por: Eldrid, Charles F. S., et al.
Publicado: (2021)

Analysis of Glycosylation and Disulfide Bonding of Wild-Type SARS-CoV-2 Spike Glycoprotein
por: Zhang, Shijian, et al.
Publicado: (2022)

Site-specific N-glycosylation Characterization of Recombinant SARS-CoV-2 Spike Proteins
por: Zhang, Yong, et al.
Publicado: (2021)

SARS-CoV-2 Glycosylated Spike Activation Mechanism - Simulations of the Full Unbiased Pathway
por: Sztain-Pedone, Terra, et al.
Publicado: (2021)

Novel bispecific human antibody platform specifically targeting a fully open spike conformation potently neutralizes multiple SARS-CoV-2 variants
por: Kim, Ji Woong, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_42piqg9gi7ps6lu2vd8kbh4bm0