Modulation of lysosomal function as a therapeutic approach for coronaviral infections

The endo-lysosomal pathway plays an important role in pathogen clearance and both bacteria and viruses have evolved complex mechanisms to evade this host system. Here, we describe a novel aspect of coronaviral infection, whereby the master transcriptional regulator of lysosome biogenesis – TFEB – is...

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Detalles Bibliográficos
Autores principales: Liu, Yuan, Lear, Travis, Larsen, Mads, Lin, Bo, Cao, Qing, Alfaras, Irene, Kennerdell, Jason, Salminen, Laura, Camarco, Daniel, Lockwood, Karina, Ma, Jing, Liu, Jie, Tan, Jay, Myerburg, Michael, Chen, Yanwen, St Croix, Claudette, Sekine, Yusuke, Evankovich, John, Finkel, Toren, Chen, Bill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132244/
https://www.ncbi.nlm.nih.gov/pubmed/34013250
http://dx.doi.org/10.21203/rs.3.rs-419305/v1

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