Plasmodium infection induces cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein

Individuals with acute malaria infection generated high levels of antibodies that cross-react with the SARS-CoV-2 Spike protein. Cross-reactive antibodies specifically recognized the sialic acid moiety on N-linked glycans of the Spike protein and do not neutralize in vitro SARS-CoV-2. Sero-surveilla...

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Autores principales: Lapidus, Sarah, Liu, Feimei, Casanovas-Massana, Arnau, Dai, Yile, Huck, John D., Lucas, Carolina, Klein, Jon, Filler, Renata B., Strine, Madison S., Sy, Mouhamad, Deme, Awa B., Badiane, Aida S., Dieye, Baba, Ndiaye, Ibrahima Mbaye, Diedhiou, Younous, Mbaye, Amadou Moctar, Diagne, Cheikh Tidiane, Vigan-Womas, Inés, Mbengue, Alassane, Sadio, Bacary D., Diagne, Moussa M., Moore, Adam J., Mangou, Khadidiatou, Diallo, Fatoumata, Sene, Seynabou D., Pouye, Mariama N., Faye, Rokhaya, Diouf, Babacar, Nery, Nivison, Costa, Federico, Reis, Mitermayer, Muenker, M. Catherine, Hodson, Daniel Z., Mbarga, Yannick, Katz, Ben Z., Andrews, Jason R., Campbell, Melissa, Srivathsan, Ariktha, Kamath, Kathy, Baum-Jones, Elisabeth, Faye, Ousmane, Sall, Amadou Alpha, Quintero Vélez, Juan Carlos, Cappello, Michael, Wilson, Michael, Ben-Mamoun, Choukri, Somé, Fabrice A., Dabiré, Roch K., Moukoko, Carole Else Eboumbou, Ouédraogo, Jean Bosco, Boum, Yap, Shon, John, Ndiaye, Daouda, Wisnewski, Adam, Parikh, Sunil, Iwasaki, Akiko, Wilen, Craig B., Ko, Albert I., Ring, Aaron M., Bei, Amy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132281/
https://www.ncbi.nlm.nih.gov/pubmed/34013301
http://dx.doi.org/10.1101/2021.05.10.21256855

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