Natural selection on synonymous mutations in SARS-CoV-2 and the impact on estimating divergence time

To adapt to human host environment, synonymous mutations in SARS-CoV-2 are shaped by tRNA selection, energy cost and RNA structure.

Detalles Bibliográficos
Autores principales: Yu, Yuanyuan, Li, Yan, Dong, Yu, Wang, Xuekun, Li, Chunxiao, Jiang, Wenqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2021
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132620/
http://dx.doi.org/10.2217/fvl-2021-0078
Descripción
Sumario:To adapt to human host environment, synonymous mutations in SARS-CoV-2 are shaped by tRNA selection, energy cost and RNA structure.

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