Cargando…

Single-cell identification by microfluidic-based in situ extracting and online mass spectrometric analysis of phospholipids expression

This work describes a microfluidic system for in situ extraction of a single-cell and its phosphatidylcholine analysis through mass spectrometry. This approach uncovered cellular heterogeneity among seemingly identical cells and provided a new platform for identification and classification of cells.

Detalles Bibliográficos
Autores principales: Huang, Qiushi, Mao, Sifeng, Khan, Mashooq, Li, Weiwei, Zhang, Qiang, Lin, Jin-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8132990/
https://www.ncbi.nlm.nih.gov/pubmed/34040719
http://dx.doi.org/10.1039/c9sc05143k
Descripción
Sumario:This work describes a microfluidic system for in situ extraction of a single-cell and its phosphatidylcholine analysis through mass spectrometry. This approach uncovered cellular heterogeneity among seemingly identical cells and provided a new platform for identification and classification of cells.