Uncatalyzed conjugate addition of organozinc halides to enones in DME: a combined experimental/computational study on the role of the solvent and the reaction mechanism

Both aryl and alkylzinc halides prepared by direct insertion of zinc into organic halides in the presence of LiCl underwent the conjugate addition reaction to nonenolizable unsaturated ketones in excellent yield, provided that DME was used instead of THF as the solvent. Diffusion NMR measurements hi...

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Detalles Bibliográficos
Autores principales: Casotti, Gianluca, Ciancaleoni, Gianluca, Lipparini, Filippo, Nieri, Chiara, Iuliano, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133023/
https://www.ncbi.nlm.nih.gov/pubmed/34040720
http://dx.doi.org/10.1039/c9sc04820k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133023/
https://www.ncbi.nlm.nih.gov/pubmed/34040720
http://dx.doi.org/10.1039/c9sc04820k

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