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Colon Crypts of Subjects With Familial Adenomatous Polyposis Show an Increased Number of LGR5+ Ectopic Stem Cells

INTRODUCTION: Familial adenomatous polyposis (FAP) is a hereditary colorectal cancer (CRC) syndrome characterized by accelerated adenoma development due to inherited (or de novo) mutations in the APC regulator of WNT signaling pathway (APC) gene. The mechanism underlying this accelerated polyp devel...

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Detalles Bibliográficos
Autores principales:	Jennelle, Lucas T., Dampier, Christopher H., Tring, Stephanie, Powell, Steven, Casey, Graham
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133103/ https://www.ncbi.nlm.nih.gov/pubmed/33999013 http://dx.doi.org/10.14309/ctg.0000000000000353

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