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Preserved intention understanding during moral judgments in schizophrenia

INTRODUCTION: Although there is convincing evidence for socio-cognitive impairments in schizophrenia spectrum disorder (SSD), little evidence is found for deficient moral cognition. We investigated whether patients with SSD showed altered moral judgments in a story task where the protagonist either...

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Autores principales: Kronbichler, Lisa, Stelzig-Schöler, Renate, Lenger, Melanie, Weber, Stefanie, Pearce, Brandy-Gale, Reich, Luise-Antonia, Aichhorn, Wolfgang, Kronbichler, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133419/
https://www.ncbi.nlm.nih.gov/pubmed/34010340
http://dx.doi.org/10.1371/journal.pone.0251180
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author Kronbichler, Lisa
Stelzig-Schöler, Renate
Lenger, Melanie
Weber, Stefanie
Pearce, Brandy-Gale
Reich, Luise-Antonia
Aichhorn, Wolfgang
Kronbichler, Martin
author_facet Kronbichler, Lisa
Stelzig-Schöler, Renate
Lenger, Melanie
Weber, Stefanie
Pearce, Brandy-Gale
Reich, Luise-Antonia
Aichhorn, Wolfgang
Kronbichler, Martin
author_sort Kronbichler, Lisa
collection PubMed
description INTRODUCTION: Although there is convincing evidence for socio-cognitive impairments in schizophrenia spectrum disorder (SSD), little evidence is found for deficient moral cognition. We investigated whether patients with SSD showed altered moral judgments in a story task where the protagonist either had a neutral or malicious intention towards another person. This paradigm examined whether SSD relates to altered moral cognition in general or specifically to impaired integration of prior information (such as beliefs) in moral judgments. METHODS: 23 patients and 32 healthy controls read vignettes created in a 2 x 2 design. The protagonist in each story either had a neutral or negative intention towards another person which, as a result, either died (negative outcome) or did not die (neutral outcome). Participants rated the moral permissibility of the protagonist’s action. Standard null hypothesis significance testing and equivalent Bayes analyses are reported. RESULTS: Schizophrenia patients did not differ significantly in permissibility ratings from healthy controls. This finding was supported by the Bayes analyses which favoured the null hypothesis. Task performance was not related to symptom severity or medication. CONCLUSIONS: The current findings do not support the notion that moral judgments are deficient in schizophrenia. Furthermore, the current study shows that patients do not have observable difficulties in integrating the protagonist’s belief in the rating of the moral permissibility of the action-outcome.
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spelling pubmed-81334192021-05-27 Preserved intention understanding during moral judgments in schizophrenia Kronbichler, Lisa Stelzig-Schöler, Renate Lenger, Melanie Weber, Stefanie Pearce, Brandy-Gale Reich, Luise-Antonia Aichhorn, Wolfgang Kronbichler, Martin PLoS One Research Article INTRODUCTION: Although there is convincing evidence for socio-cognitive impairments in schizophrenia spectrum disorder (SSD), little evidence is found for deficient moral cognition. We investigated whether patients with SSD showed altered moral judgments in a story task where the protagonist either had a neutral or malicious intention towards another person. This paradigm examined whether SSD relates to altered moral cognition in general or specifically to impaired integration of prior information (such as beliefs) in moral judgments. METHODS: 23 patients and 32 healthy controls read vignettes created in a 2 x 2 design. The protagonist in each story either had a neutral or negative intention towards another person which, as a result, either died (negative outcome) or did not die (neutral outcome). Participants rated the moral permissibility of the protagonist’s action. Standard null hypothesis significance testing and equivalent Bayes analyses are reported. RESULTS: Schizophrenia patients did not differ significantly in permissibility ratings from healthy controls. This finding was supported by the Bayes analyses which favoured the null hypothesis. Task performance was not related to symptom severity or medication. CONCLUSIONS: The current findings do not support the notion that moral judgments are deficient in schizophrenia. Furthermore, the current study shows that patients do not have observable difficulties in integrating the protagonist’s belief in the rating of the moral permissibility of the action-outcome. Public Library of Science 2021-05-19 /pmc/articles/PMC8133419/ /pubmed/34010340 http://dx.doi.org/10.1371/journal.pone.0251180 Text en © 2021 Kronbichler et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Kronbichler, Lisa
Stelzig-Schöler, Renate
Lenger, Melanie
Weber, Stefanie
Pearce, Brandy-Gale
Reich, Luise-Antonia
Aichhorn, Wolfgang
Kronbichler, Martin
Preserved intention understanding during moral judgments in schizophrenia
title Preserved intention understanding during moral judgments in schizophrenia
title_full Preserved intention understanding during moral judgments in schizophrenia
title_fullStr Preserved intention understanding during moral judgments in schizophrenia
title_full_unstemmed Preserved intention understanding during moral judgments in schizophrenia
title_short Preserved intention understanding during moral judgments in schizophrenia
title_sort preserved intention understanding during moral judgments in schizophrenia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133419/
https://www.ncbi.nlm.nih.gov/pubmed/34010340
http://dx.doi.org/10.1371/journal.pone.0251180
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