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Quality of life in people living with HIV-associated neurocognitive disorder: A scoping review study

Quality of life (QoL) is recognized as an essential end point in the disease management of chronic conditions such as HIV with calls to include good QoL as a ‘fourth 90’ in the 90-90-90 testing and treatment targets introduced by World Health Organization in 2016. Cognitive impairments impact a broa...

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Autores principales: Alford, Kate, Daley, Stephanie, Banerjee, Sube, Vera, Jaime H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133427/
https://www.ncbi.nlm.nih.gov/pubmed/34010362
http://dx.doi.org/10.1371/journal.pone.0251944
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author Alford, Kate
Daley, Stephanie
Banerjee, Sube
Vera, Jaime H.
author_facet Alford, Kate
Daley, Stephanie
Banerjee, Sube
Vera, Jaime H.
author_sort Alford, Kate
collection PubMed
description Quality of life (QoL) is recognized as an essential end point in the disease management of chronic conditions such as HIV with calls to include good QoL as a ‘fourth 90’ in the 90-90-90 testing and treatment targets introduced by World Health Organization in 2016. Cognitive impairments impact a broad spectrum of experiences and are a common issue effecting people living with HIV (PLWH). Despite this, few studies have examined QoL in PLWH who also have a cognitive disorder. This study aimed to synthesize and describe what is known about QoL in those living with HIV-associated neurocognitive disorders (HAND). A scoping review of peer-reviewed literature was conducted to identify how QoL has been investigated and measured in PLWH with HAND, and how PLWH with HAND report and describe their QoL. We searched PsychInfo, Medline, Scopus, and Web of Science along with hand-searching reference lists from relevant studies found. Included studies were those published in English after 1(st) January 2003 which included PLWH with cognitive impairment not due to other pre-existing conditions. Fifteen articles met criteria for inclusion. Two studies measured QoL as a primary aim, with others including QoL assessment as part of a broader battery of outcomes. The MOS-HIV and SF-36 were the most commonly used measures of overall QoL, with findings generally suggestive of poorer overall QoL in PLWH with HAND, compared to PLWH without cognitive impairment. Studies which examined dimensions of QoL focused exclusively on functionality, level of independence, and psychological QoL domains. There is a considerable dearth of research examining QoL in PLWH with HAND. The initiatives which advocate for healthy aging and improved QoL in PLWH must be extended to include and understand the experiences those also living with cognitive impairment. Research is needed to understand the broad experiential impacts of living with these two complex, chronic conditions, to ensure interventions are meaningful to patients and potential benefits are not missed.
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spelling pubmed-81334272021-05-27 Quality of life in people living with HIV-associated neurocognitive disorder: A scoping review study Alford, Kate Daley, Stephanie Banerjee, Sube Vera, Jaime H. PLoS One Research Article Quality of life (QoL) is recognized as an essential end point in the disease management of chronic conditions such as HIV with calls to include good QoL as a ‘fourth 90’ in the 90-90-90 testing and treatment targets introduced by World Health Organization in 2016. Cognitive impairments impact a broad spectrum of experiences and are a common issue effecting people living with HIV (PLWH). Despite this, few studies have examined QoL in PLWH who also have a cognitive disorder. This study aimed to synthesize and describe what is known about QoL in those living with HIV-associated neurocognitive disorders (HAND). A scoping review of peer-reviewed literature was conducted to identify how QoL has been investigated and measured in PLWH with HAND, and how PLWH with HAND report and describe their QoL. We searched PsychInfo, Medline, Scopus, and Web of Science along with hand-searching reference lists from relevant studies found. Included studies were those published in English after 1(st) January 2003 which included PLWH with cognitive impairment not due to other pre-existing conditions. Fifteen articles met criteria for inclusion. Two studies measured QoL as a primary aim, with others including QoL assessment as part of a broader battery of outcomes. The MOS-HIV and SF-36 were the most commonly used measures of overall QoL, with findings generally suggestive of poorer overall QoL in PLWH with HAND, compared to PLWH without cognitive impairment. Studies which examined dimensions of QoL focused exclusively on functionality, level of independence, and psychological QoL domains. There is a considerable dearth of research examining QoL in PLWH with HAND. The initiatives which advocate for healthy aging and improved QoL in PLWH must be extended to include and understand the experiences those also living with cognitive impairment. Research is needed to understand the broad experiential impacts of living with these two complex, chronic conditions, to ensure interventions are meaningful to patients and potential benefits are not missed. Public Library of Science 2021-05-19 /pmc/articles/PMC8133427/ /pubmed/34010362 http://dx.doi.org/10.1371/journal.pone.0251944 Text en © 2021 Alford et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Alford, Kate
Daley, Stephanie
Banerjee, Sube
Vera, Jaime H.
Quality of life in people living with HIV-associated neurocognitive disorder: A scoping review study
title Quality of life in people living with HIV-associated neurocognitive disorder: A scoping review study
title_full Quality of life in people living with HIV-associated neurocognitive disorder: A scoping review study
title_fullStr Quality of life in people living with HIV-associated neurocognitive disorder: A scoping review study
title_full_unstemmed Quality of life in people living with HIV-associated neurocognitive disorder: A scoping review study
title_short Quality of life in people living with HIV-associated neurocognitive disorder: A scoping review study
title_sort quality of life in people living with hiv-associated neurocognitive disorder: a scoping review study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133427/
https://www.ncbi.nlm.nih.gov/pubmed/34010362
http://dx.doi.org/10.1371/journal.pone.0251944
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