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iMAP: A Web Server for Metabolomics Data Integrative Analysis

Metabolomics data analysis depends on the utilization of bioinformatics tools. To meet the evolving needs of metabolomics research, several integrated platforms have been developed. Our group has developed a desktop platform IP4M (integrated Platform for Metabolomics Data Analysis) which allows user...

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Detalles Bibliográficos
Autores principales: Zhou, Di, Zhu, Wenjia, Sun, Tao, Wang, Yang, Chi, Yi, Chen, Tianlu, Lin, Jingchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133432/
https://www.ncbi.nlm.nih.gov/pubmed/34026726
http://dx.doi.org/10.3389/fchem.2021.659656
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author Zhou, Di
Zhu, Wenjia
Sun, Tao
Wang, Yang
Chi, Yi
Chen, Tianlu
Lin, Jingchao
author_facet Zhou, Di
Zhu, Wenjia
Sun, Tao
Wang, Yang
Chi, Yi
Chen, Tianlu
Lin, Jingchao
author_sort Zhou, Di
collection PubMed
description Metabolomics data analysis depends on the utilization of bioinformatics tools. To meet the evolving needs of metabolomics research, several integrated platforms have been developed. Our group has developed a desktop platform IP4M (integrated Platform for Metabolomics Data Analysis) which allows users to perform a nearly complete metabolomics data analysis in one-stop. With the extensive usage of IP4M, more and more demands were raised from users worldwide for a web version and a more customized workflow. Thus, iMAP (integrated Metabolomics Analysis Platform) was developed with extended functions, improved performances, and redesigned structures. Compared with existing platforms, iMAP has more methods and usage modes. A new module was developed with an automatic pipeline for train-test set separation, feature selection, and predictive model construction and validation. A new module was incorporated with sufficient editable parameters for network construction, visualization, and analysis. Moreover, plenty of plotting tools have been upgraded for highly customized publication-ready figures. Overall, iMAP is a good alternative tool with complementary functions to existing metabolomics data analysis platforms. iMAP is freely available for academic usage at https://imap.metaboprofile.cloud/ (License MPL 2.0).
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spelling pubmed-81334322021-05-20 iMAP: A Web Server for Metabolomics Data Integrative Analysis Zhou, Di Zhu, Wenjia Sun, Tao Wang, Yang Chi, Yi Chen, Tianlu Lin, Jingchao Front Chem Chemistry Metabolomics data analysis depends on the utilization of bioinformatics tools. To meet the evolving needs of metabolomics research, several integrated platforms have been developed. Our group has developed a desktop platform IP4M (integrated Platform for Metabolomics Data Analysis) which allows users to perform a nearly complete metabolomics data analysis in one-stop. With the extensive usage of IP4M, more and more demands were raised from users worldwide for a web version and a more customized workflow. Thus, iMAP (integrated Metabolomics Analysis Platform) was developed with extended functions, improved performances, and redesigned structures. Compared with existing platforms, iMAP has more methods and usage modes. A new module was developed with an automatic pipeline for train-test set separation, feature selection, and predictive model construction and validation. A new module was incorporated with sufficient editable parameters for network construction, visualization, and analysis. Moreover, plenty of plotting tools have been upgraded for highly customized publication-ready figures. Overall, iMAP is a good alternative tool with complementary functions to existing metabolomics data analysis platforms. iMAP is freely available for academic usage at https://imap.metaboprofile.cloud/ (License MPL 2.0). Frontiers Media S.A. 2021-05-05 /pmc/articles/PMC8133432/ /pubmed/34026726 http://dx.doi.org/10.3389/fchem.2021.659656 Text en Copyright © 2021 Zhou, Zhu, Sun, Wang, Chi, Chen and Lin. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Zhou, Di
Zhu, Wenjia
Sun, Tao
Wang, Yang
Chi, Yi
Chen, Tianlu
Lin, Jingchao
iMAP: A Web Server for Metabolomics Data Integrative Analysis
title iMAP: A Web Server for Metabolomics Data Integrative Analysis
title_full iMAP: A Web Server for Metabolomics Data Integrative Analysis
title_fullStr iMAP: A Web Server for Metabolomics Data Integrative Analysis
title_full_unstemmed iMAP: A Web Server for Metabolomics Data Integrative Analysis
title_short iMAP: A Web Server for Metabolomics Data Integrative Analysis
title_sort imap: a web server for metabolomics data integrative analysis
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133432/
https://www.ncbi.nlm.nih.gov/pubmed/34026726
http://dx.doi.org/10.3389/fchem.2021.659656
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