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Chronic stimulation of group II metabotropic glutamate receptors in the medulla oblongata attenuates hypertension development in spontaneously hypertensive rats

Baroreflex dysfunction is partly implicated in hypertension and one responsible region is the dorsal medulla oblongata including the nucleus tractus solitarius (NTS). NTS neurons receive and project glutamatergic inputs to subsequently regulate blood pressure, while G-protein-coupled metabotropic gl...

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Detalles Bibliográficos
Autores principales: Hsu, Julia Chu-Ning, Sekizawa, Shin-ichi, Tochinai, Ryota, Kuwahara, Masayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133461/
https://www.ncbi.nlm.nih.gov/pubmed/34010316
http://dx.doi.org/10.1371/journal.pone.0251495