Direct derivation of human alveolospheres for SARS-CoV-2 infection modeling and drug screening

Although the main cellular target of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is thought to be alveolar cells, the absence of their tractable culture system precludes the development of a clinically relevant SARS-CoV-2 infection model. Here, we establish an efficient hu...

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Detalles Bibliográficos
Autores principales: Ebisudani, Toshiki, Sugimoto, Shinya, Haga, Kei, Mitsuishi, Akifumi, Takai-Todaka, Reiko, Fujii, Masayuki, Toshimitsu, Kohta, Hamamoto, Junko, Sugihara, Kai, Hishida, Tomoyuki, Asamura, Hisao, Fukunaga, Koichi, Yasuda, Hiroyuki, Katayama, Kazuhiko, Sato, Toshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8133488/
https://www.ncbi.nlm.nih.gov/pubmed/34038715
http://dx.doi.org/10.1016/j.celrep.2021.109218

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