Cargando…

Automated enumeration and phenotypic characterization of CTCs and tdEVs in patients with metastatic castration resistant prostate cancer

BACKGROUND: Although most patients with metastatic castration-resistant prostate cancer (mCRPC) initially benefit from treatment with androgen receptor signaling inhibitors (ARSi), resistance inevitably occurs. Hence, we investigated the prognostic value of automated circulating tumor cell (CTC) and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oeyen, Steffi, Liégeois, Vincent, De Laere, Bram, Buys, Andy, Strijbos, Michiel, Dirix, Piet, Meijnders, Paul, Vermeulen, Peter, Van Laere, Steven, Dirix, Luc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134056/ https://www.ncbi.nlm.nih.gov/pubmed/33230201 http://dx.doi.org/10.1038/s41391-020-00304-1

Ejemplares similares

Circulating tumor cell detection: A prospective comparison between CellSearch® and RareCyte® platforms in patients with progressive metastatic breast cancer
por: Dirix, Luc, et al.
Publicado: (2022)

Coagulation/fibrinolysis and circulating tumor cells in patients with advanced breast cancer
por: Dirix, Luc Y., et al.
Publicado: (2022)

A phase I dose-escalation trial of stereotactic ablative body radiotherapy for non-spine bone and lymph node metastases (DESTROY-trial)
por: Mercier, Carole, et al.
Publicado: (2018)

Precision of image-guided spinal stereotactic ablative radiotherapy and impact of positioning variables
por: Billiet, Charlotte, et al.
Publicado: (2022)

Molecular profiles to biology and pathways: a systems biology approach
por: Van Laere, Steven, et al.
Publicado: (2016)

Increased Pathway Complexity Is a Prognostic Biomarker in Metastatic Castration-Resistant Prostate Cancer
por: De Laere, Bram, et al.
Publicado: (2021)

Inflammatory breast carcinoma as a model of accelerated self-metastatic expansion by intravascular growth
por: Vermeulen, P B, et al.
Publicado: (2009)

Outcome and toxicity of hypofractionated image-guided SABR for spinal oligometastases
por: Billiet, Charlotte, et al.
Publicado: (2020)

Evaluation and consequences of heterogeneity in the circulating tumor cell compartment
por: Brouwer, Anja, et al.
Publicado: (2016)

Combinatorial Power of cfDNA, CTCs and EVs in Oncology
por: Keup, Corinna, et al.
Publicado: (2022)

Evaluation of a marker independent isolation method for circulating tumor cells in esophageal adenocarcinoma
por: Philippron, Annouck, et al.
Publicado: (2021)

Challenges in enumeration of CTCs in breast cancer using techniques independent of cytokeratin expression
por: Castle, John, et al.
Publicado: (2017)

The use of simulation-CT’s as a coronavirus disease 2019 screening tool during the severe acute respiratory syndrome coronavirus 2 pandemic()
por: Nevens, Daan, et al.
Publicado: (2020)

Dysregulation of microRNAs in breast cancer and their potential role as prognostic and predictive biomarkers in patient management
por: van Schooneveld, Eleni, et al.
Publicado: (2015)

Integrated miRNA and mRNA expression profiling of the inflammatory breast cancer subtype
por: Van der Auwera, I, et al.
Publicado: (2010)

Cell-free DNA profiling of metastatic prostate cancer reveals microsatellite instability, structural rearrangements and clonal hematopoiesis
por: Mayrhofer, Markus, et al.
Publicado: (2018)

HER-2 status of circulating tumor cells in a metastatic breast cancer cohort: A comparative study on characterization techniques
por: Brouwer, Anja, et al.
Publicado: (2019)

The interaction between ER and NFκB in resistance to endocrine therapy
por: Sas, Leen, et al.
Publicado: (2012)

NOTCH and DNA repair pathways are more frequently targeted by genomic alterations in inflammatory than in non‐inflammatory breast cancers
por: Bertucci, François, et al.
Publicado: (2020)

Real-time RT–PCR correlates with immunocytochemistry for the detection of disseminated epithelial cells in bone marrow aspirates of patients with breast cancer
por: Benoy, I H, et al.
Publicado: (2004)

Distinct molecular phenotype of inflammatory breast cancer compared to non-inflammatory breast cancer using Affymetrix-based genome-wide gene-expression analysis
por: Van Laere, S, et al.
Publicado: (2007)

NF-κB activation in inflammatory breast cancer is associated with oestrogen receptor downregulation, secondary to EGFR and/or ErbB2 overexpression and MAPK hyperactivation
por: Van Laere, S J, et al.
Publicado: (2007)

PDL1 expression in inflammatory breast cancer is frequent and predicts for the pathological response to chemotherapy
por: Bertucci, François, et al.
Publicado: (2015)

AR splice variants in circulating tumor cells of patients with castration‐resistant prostate cancer: relation with outcome to cabazitaxel
por: Sieuwerts, Anieta M., et al.
Publicado: (2019)

Study Assessing the Quality of Quantification of Estrogen Receptor Protein Expression by Immunohistochemistry and Gene Expression in Breast Cancer
por: Leen, Sas, et al.
Publicado: (2014)

The presence of circulating total DNA and methylated genes is associated with circulating tumour cells in blood from breast cancer patients
por: Van der Auwera, I, et al.
Publicado: (2009)

Semiautomated isolation and molecular characterisation of single or highly purified tumour cells from CellSearch enriched blood samples using dielectrophoretic cell sorting
por: Peeters, D J E, et al.
Publicado: (2013)

Distinguishing blood and lymph vessel invasion in breast cancer: a prospective immunohistochemical study
por: Van den Eynden, G G, et al.
Publicado: (2006)

A Core Invasiveness Gene Signature Reflects Epithelial-to-Mesenchymal Transition but Not Metastatic Potential in Breast Cancer Cell Lines and Tissue Samples
por: Marsan, Melike, et al.
Publicado: (2014)

A phase III randomized-controlled, single-blind trial to improve quality of life with stereotactic body radiotherapy for patients with painful bone metastases (ROBOMET)
por: Mercier, Carole, et al.
Publicado: (2019)

Induction of lymphangiogenesis in and around axillary lymph node metastases of patients with breast cancer
por: Van den Eynden, G G, et al.
Publicado: (2006)

Circulating tumour cell detection: a direct comparison between the CellSearch System, the AdnaTest and CK-19/mammaglobin RT–PCR in patients with metastatic breast cancer
por: Van der Auwera, I, et al.
Publicado: (2010)

Quantitative methylation profiling in tumor and matched morphologically normal tissues from breast cancer patients
por: Van der Auwera, Ilse, et al.
Publicado: (2010)

Array-Based DNA Methylation Profiling for Breast Cancer Subtype Discrimination
por: Van der Auwera, Ilse, et al.
Publicado: (2010)

EV-origin: Enumerating the tissue-cellular origin of circulating extracellular vesicles using exLR profile
por: Li, Yuchen, et al.
Publicado: (2020)

AR and PI3K Genomic Profiling of Cell-free DNA Can Identify Poor Responders to Lutetium-177-PSMA Among Patients with Metastatic Castration-resistant Prostate Cancer
por: Vanwelkenhuyzen, Jan, et al.
Publicado: (2023)

Comparative Profiling of Metastatic 4T1- vs. Non-metastatic Py230-Based Mammary Tumors in an Intraductal Model for Triple-Negative Breast Cancer
por: Steenbrugge, Jonas, et al.
Publicado: (2019)

Expression profiling of cancerous and normal breast tissues identifies microRNAs that are differentially expressed in serum from patients with (metastatic) breast cancer and healthy volunteers
por: van Schooneveld, Eleni, et al.
Publicado: (2012)

Infiltrating stromal immune cells in inflammatory breast cancer are associated with an improved outcome and increased PD-L1 expression
por: Van Berckelaer, C., et al.
Publicado: (2019)

The role of apoptotic cell death in the radiosensitising effect of gemcitabine
por: Pauwels, B, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_t2dqbuoamok5mjp6561utu5akn