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Extended single-dose toxicity study of [(211)At]NaAt in mice for the first-in-human clinical trial of targeted alpha therapy for differentiated thyroid cancer

OBJECTIVE: Astatine ((211)At) is a promising alpha emitter as an alternative to iodine ((131)I). We are preparing the first-in-human (FIH) clinical trial of targeted alpha therapy for differentiated thyroid cancer in consultation with Pharmaceuticals and Medical Devices Agency. Here, we performed an...

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Detalles Bibliográficos
Autores principales:	Watabe, Tadashi, Kaneda-Nakashima, Kazuko, Ooe, Kazuhiro, Liu, Yuwei, Kurimoto, Kenta, Murai, Takashi, Shidahara, Yuka, Okuma, Kenji, Takeuchi, Masanori, Nishide, Masayuki, Toyoshima, Atsushi, Shinohara, Atsushi, Shirakami, Yoshifumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Singapore 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134311/ https://www.ncbi.nlm.nih.gov/pubmed/33871803 http://dx.doi.org/10.1007/s12149-021-01612-9

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