MYCN mediates TFRC-dependent ferroptosis and reveals vulnerabilities in neuroblastoma

MYCN amplification is tightly associated with the poor prognosis of pediatric neuroblastoma (NB). The regulation of NB cell death by MYCN represents an important aspect, as it directly contributes to tumor progression and therapeutic resistance. However, the relationship between MYCN and cell death...

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Detalles Bibliográficos
Autores principales: Lu, Yuxiong, Yang, Qing, Su, Yubin, Ji, Yin, Li, Guobang, Yang, Xianzhi, Xu, Liyan, Lu, Zhaoliang, Dong, Jiajun, Wu, Yi, Bei, Jin-Xin, Pan, Chaoyun, Gu, Xiaoqiong, Li, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134466/
https://www.ncbi.nlm.nih.gov/pubmed/34011924
http://dx.doi.org/10.1038/s41419-021-03790-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134466/
https://www.ncbi.nlm.nih.gov/pubmed/34011924
http://dx.doi.org/10.1038/s41419-021-03790-w

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