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MYCN mediates TFRC-dependent ferroptosis and reveals vulnerabilities in neuroblastoma
MYCN amplification is tightly associated with the poor prognosis of pediatric neuroblastoma (NB). The regulation of NB cell death by MYCN represents an important aspect, as it directly contributes to tumor progression and therapeutic resistance. However, the relationship between MYCN and cell death...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134466/ https://www.ncbi.nlm.nih.gov/pubmed/34011924 http://dx.doi.org/10.1038/s41419-021-03790-w |