Cargando…

Anti-TNF-α agents Modulate SARS-CoV-2 Receptors and Increase the Risk of Infection Through Notch-1 Signaling

Although millions of patients with underlining conditions are treated primarily with anti-TNF-α agents, little is known about the safety of this standard therapy during the coronavirus disease-2019 (COVID-19) pandemic. In this study, we investigated the effect of anti-TNF-α monoclonal antibodies on...

Descripción completa

Detalles Bibliográficos
Autores principales:	Keewan, Esra’a, Beg, Shazia, Naser, Saleh A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134694/ https://www.ncbi.nlm.nih.gov/pubmed/34025650 http://dx.doi.org/10.3389/fimmu.2021.641295

Ejemplares similares

Notch-1 Signaling Modulates Macrophage Polarization and Immune Defense against Mycobacterium avium paratuberculosis Infection in Inflammatory Diseases
por: Keewan, Esra’a, et al.
Publicado: (2020)

The Role of Notch Signaling in Macrophages during Inflammation and Infection: Implication in Rheumatoid Arthritis?
por: Keewan, Esra’a, et al.
Publicado: (2020)

MiR-146a rs2910164 G > C polymorphism modulates Notch-1/IL-6 signaling during infection: a possible risk factor for Crohn’s disease
por: Keewan, Esra’a, et al.
Publicado: (2020)

Attenuation of Excess TNF-α Release in Crohn’s Disease by Silencing of iRHOMs 1/2 and the Restoration of TGF-β Mediated Immunosuppression Through Modulation of TACE Trafficking
por: Louis, Taylor J., et al.
Publicado: (2022)

TNFα aggravates detrimental effects of SARS-CoV-2 infection in the liver
por: Lücke, Jöran, et al.
Publicado: (2023)

Methotrexate Enhances Apoptosis of Transmembrane TNF-Expressing Cells Treated With Anti-TNF Agents
por: Wang, Qiaolei, et al.
Publicado: (2020)

The Emerging Role of Suppressors of Cytokine Signaling (SOCS) in the Development and Progression of Leukemia
por: Keewan, Esra’a, et al.
Publicado: (2021)

Polymorphisms in TNF Receptor Superfamily 1B (TNFRSF1B:rs3397) are Linked to Mycobacterium avium paratuberculosis Infection and Osteoporosis in Rheumatoid Arthritis
por: Naser, Amna, et al.
Publicado: (2019)

Ozoralizumab, a Humanized Anti-TNFα NANOBODY(®) Compound, Exhibits Efficacy Not Only at the Onset of Arthritis in a Human TNF Transgenic Mouse but Also During Secondary Failure of Administration of an Anti-TNFα IgG
por: Ishiwatari-Ogata, Chihiro, et al.
Publicado: (2022)

The Role of TNF-α and Anti-TNF-α Agents during Preconception, Pregnancy, and Breastfeeding
por: Romanowska-Próchnicka, Katarzyna, et al.
Publicado: (2021)

TNF-α Inhibitors and Other Biologic Agents for the Treatment of Immune Checkpoint Inhibitor-Induced Myocarditis
por: Liu, Xiaohang, et al.
Publicado: (2022)

Immunological Changes in Blood of Newborns Exposed to Anti-TNF-α during Pregnancy
por: Esteve-Solé, Ana, et al.
Publicado: (2017)

Tuberculosis Risk Stratification of Psoriatic Patients Before Anti-TNF-α Treatment
por: Benhadou, Farida, et al.
Publicado: (2021)

Transmembrane TNF-α: structure, function and interaction with anti-TNF agents
por: Horiuchi, Takahiko, et al.
Publicado: (2010)

Modulation of Regulatory T Cell Activity by TNF Receptor Type II-Targeting Pharmacological Agents
por: Zou, Huimin, et al.
Publicado: (2018)

Immunogenicity of Anti-TNF-α Biotherapies: I. Individualized Medicine Based on Immunopharmacological Evidence
por: Bendtzen, Klaus
Publicado: (2015)

Metabolic Reprogramming and Cell Adhesion in Acute Leukemia Adaptation to the CNS Niche
por: Sharma, Nitesh D., et al.
Publicado: (2021)

Immunogenicity of Anti-TNF-α Biotherapies: II. Clinical Relevance of Methods Used for Anti-Drug Antibody Detection
por: Bendtzen, Klaus
Publicado: (2015)

Notch Signaling Modulates Macrophage Polarization and Phagocytosis Through Direct Suppression of Signal Regulatory Protein α Expression
por: Lin, Yan, et al.
Publicado: (2018)

Notch1 Modulation of Cellular Calcium Regulates Mitochondrial Metabolism and Anti-Apoptotic Activity in T-Regulatory Cells
por: Saini, Neetu, et al.
Publicado: (2022)

Can We Predict the Efficacy of Anti-TNF-α Agents?
por: Lopetuso, Loris Riccardo, et al.
Publicado: (2017)

Anti-PD-1 immunotherapy leads to tuberculosis reactivation via dysregulation of TNF-α
por: Tezera, Liku B, et al.
Publicado: (2020)

Molecular Landscape of Anti-Drug Antibodies Reveals the Mechanism of the Immune Response Following Treatment With TNFα Antagonists
por: Vaisman-Mentesh, Anna, et al.
Publicado: (2019)

TNFα-Signaling Modulates the Kinase Activity of Human Effector Treg and Regulates IL-17A Expression
por: Urbano, Paulo C. M., et al.
Publicado: (2020)

Whole Transcriptome Analysis Reveals That Filifactor alocis Modulates TNFα-Stimulated MAPK Activation in Human Neutrophils
por: Miralda, Irina, et al.
Publicado: (2020)

Classical and Paradoxical Effects of TNF-α on Bone Homeostasis
por: Osta, Bilal, et al.
Publicado: (2014)

Changes in dietary habits and eating behaviors during COVID-19 induced confinement: A study from Jordan
por: Alomari, Mahmoud A., et al.
Publicado: (2022)

Role of PTPN2/22 polymorphisms in pathophysiology of Crohn’s disease
por: Sharp, Robert C, et al.
Publicado: (2018)

Polymorphisms in Protein Tyrosine Phosphatase Non-receptor Type 2 and 22 (PTPN2/22) Are Linked to Hyper-Proliferative T-Cells and Susceptibility to Mycobacteria in Rheumatoid Arthritis
por: Sharp, Robert C., et al.
Publicado: (2018)

No effect of anti-TNF-α treatment on serum IL-17 in patients with rheumatoid arthritis
por: Sikorska, Dorota, et al.
Publicado: (2018)

TNF and anti-TNF agents in Behçet's disease
por: Calamia, KT
Publicado: (2003)

GM-CSF and IL-3 Modulate Human Monocyte TNF-α Production and Renewal in In Vitro Models of Trained Immunity
por: Borriello, Francesco, et al.
Publicado: (2017)

Are Fried Foods Unhealthy? The Dietary Peroxidized Fatty Acid, 13-HPODE, Induces Intestinal Inflammation In Vitro and In Vivo
por: Keewan, Esra’a, et al.
Publicado: (2020)

Can anti-TNFα Antibodies Affect SARS-CoV-2 Disease Outcomes?
por: Khazdair, Mohammad Reza
Publicado: (2022)

Systematic review and meta-analysis on the association of tuberculosis in Crohn’s disease patients treated with tumor necrosis factor-α inhibitors (Anti-TNFα)
por: Cao, Brent L, et al.
Publicado: (2018)

Effectiveness of anti-TNF-α agents in the treatment of refractory juvenile dermatomyositis
por: Boulter, EL, et al.
Publicado: (2011)

The dichotomous outcomes of TNFα signaling in CD4(+) T cells
por: Skartsis, Nikolaos, et al.
Publicado: (2022)

TNF-α enhances sensory DRG neuron excitability through modulation of P2X3 receptors in an acute colitis model
por: Valdez-Morales, Eduardo E., et al.
Publicado: (2022)

Serum adiponectin as a predictor of laboratory response to anti-TNF-α therapy in rheumatoid arthritis
por: Sikorska, Dorota, et al.
Publicado: (2018)

The recombinant anti-TNF-α fusion protein ameliorates rheumatoid arthritis by the protective role of autophagy
por: Chen, Xiaole, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_hktulkf2ddtpcvueldjeqlalmi