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A review on the food digestion in the digestive tract and the used in vitro models
It is crucial to replicate or mimic the human digestive system conditions closely in model systems to have the food digestion-related data as accurate as possible. Thus, the data obtained could contribute to studies like those on the relationship between health and nutrition. This review aims to exp...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134715/ https://www.ncbi.nlm.nih.gov/pubmed/34027433 http://dx.doi.org/10.1016/j.crfs.2021.04.004 |
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author | Sensoy, Ilkay |
author_facet | Sensoy, Ilkay |
author_sort | Sensoy, Ilkay |
collection | PubMed |
description | It is crucial to replicate or mimic the human digestive system conditions closely in model systems to have the food digestion-related data as accurate as possible. Thus, the data obtained could contribute to studies like those on the relationship between health and nutrition. This review aims to express the human digestion system’s role in food digestion and compare the capability of the models used in simulations, especially the dynamic in vitro models. Activities of the human digestive system governing food digestion and the food matrix’s disintegration mechanism in the digestive system were discussed. Dynamic in vitro models and their relevance to the human digestive system were described. Advancements in the last 20 years, as well as limitations of those artificial systems, with prospects, were discussed. Extensive use and improvement on these models will extend our knowledge of the food matrix and digestive system’s complex interaction. Thus, it will be possible to design next-generation foods with improved health benefits. |
format | Online Article Text |
id | pubmed-8134715 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-81347152021-05-21 A review on the food digestion in the digestive tract and the used in vitro models Sensoy, Ilkay Curr Res Food Sci Review Article It is crucial to replicate or mimic the human digestive system conditions closely in model systems to have the food digestion-related data as accurate as possible. Thus, the data obtained could contribute to studies like those on the relationship between health and nutrition. This review aims to express the human digestion system’s role in food digestion and compare the capability of the models used in simulations, especially the dynamic in vitro models. Activities of the human digestive system governing food digestion and the food matrix’s disintegration mechanism in the digestive system were discussed. Dynamic in vitro models and their relevance to the human digestive system were described. Advancements in the last 20 years, as well as limitations of those artificial systems, with prospects, were discussed. Extensive use and improvement on these models will extend our knowledge of the food matrix and digestive system’s complex interaction. Thus, it will be possible to design next-generation foods with improved health benefits. Elsevier 2021-04-14 /pmc/articles/PMC8134715/ /pubmed/34027433 http://dx.doi.org/10.1016/j.crfs.2021.04.004 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Sensoy, Ilkay A review on the food digestion in the digestive tract and the used in vitro models |
title | A review on the food digestion in the digestive tract and the used in vitro models |
title_full | A review on the food digestion in the digestive tract and the used in vitro models |
title_fullStr | A review on the food digestion in the digestive tract and the used in vitro models |
title_full_unstemmed | A review on the food digestion in the digestive tract and the used in vitro models |
title_short | A review on the food digestion in the digestive tract and the used in vitro models |
title_sort | review on the food digestion in the digestive tract and the used in vitro models |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134715/ https://www.ncbi.nlm.nih.gov/pubmed/34027433 http://dx.doi.org/10.1016/j.crfs.2021.04.004 |
work_keys_str_mv | AT sensoyilkay areviewonthefooddigestioninthedigestivetractandtheusedinvitromodels AT sensoyilkay reviewonthefooddigestioninthedigestivetractandtheusedinvitromodels |