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Silencing a disintegrin and metalloproteinase-33 attenuates the proliferation of vascular smooth muscle cells via PI3K/AKT pathway: Implications in the pathogenesis of airway vascular remodeling

Accumulating evidence suggests that pulmonary expression of a disintegrin and metalloproteinase-33 (ADAM33) serves a key role in the pathogenesis of airway remodeling-related diseases, including asthma. Airway vascular proliferation has been recognized as a key feature of airway remodeling. Our prev...

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Detalles Bibliográficos
Autores principales: Yan, Fang, Hao, Yanyan, Gong, Xinji, Sun, Hu, Ding, Jianbing, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134872/
https://www.ncbi.nlm.nih.gov/pubmed/33982767
http://dx.doi.org/10.3892/mmr.2021.12141