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LY-294002 enhances the chemosensitivity of liver cancer to oxaliplatin by blocking the PI3K/AKT/HIF-1α pathway

Liver cancer remains one of the leading causes of cancer deaths worldwide. The therapeutic effect of oxaliplatin on liver cancer is often limited by acquired resistance of the cancer cells. Abnormal activation of the PI3K/AKT pathway plays an important role in the acquired resistance of oxaliplatin....

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Detalles Bibliográficos
Autores principales:	Xu, Ruyue, Zhang, Yinci, Li, Amin, Ma, Yongfang, Cai, Wenpeng, Song, Li, Xie, Yinghai, Zhou, Shuping, Cao, Weiya, Tang, Xiaolong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134878/ https://www.ncbi.nlm.nih.gov/pubmed/33982772 http://dx.doi.org/10.3892/mmr.2021.12147

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