Observational Cross-Sectional Study of Inflammatory Markers After Transient Ischemic Attacks, Acute Coronary Syndromes, and Vascular Stroke Events

We identified the prevalence of elevated high-sensitivity C-reactive protein and interleukin-6 in patients with recent cardiovascular (CV) events with or without prediabetes/diabetes, and in a control group of patients with remote CV events. Interleukin-6 was elevated in patients with prediabetes/di...

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Detalles Bibliográficos
Autores principales: Boczar, Kevin E., Liu, Peter, Chong, Aun Yeong, So, Derek, Dowlatshahi, Dar, Rayner, Katey, Beanlands, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Emerging Evidence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8134934/
https://www.ncbi.nlm.nih.gov/pubmed/34027372
http://dx.doi.org/10.1016/j.cjco.2020.12.020
Descripción
Sumario:We identified the prevalence of elevated high-sensitivity C-reactive protein and interleukin-6 in patients with recent cardiovascular (CV) events with or without prediabetes/diabetes, and in a control group of patients with remote CV events. Interleukin-6 was elevated in patients with prediabetes/diabetes and recent CV events (median, 4.84 pg/mL; interquartile range, 3.27-7.45) compared with patients with remote events (2.36 pg/mL; interquartile range, 1.09-4.00). There was a trend for elevated high-sensitivity C-reactive protein in patients with acute events and prediabetes/diabetes (P = 0.147). This supports the notion that patients with prediabetes/diabetes and recent CV events have higher inflammatory burdens than patients without recent CV events or dysglycemia.

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