sFLT01 modulates invasion and metastasis in prostate cancer DU145 cells by inhibition of VEGF/GRP78/MMP2&9 axis

BACKGROUND: About 90% of cancer-related deaths are due to metastasis of cancer cells, and angiogenesis is a critical step in this process. sFLT01 is a novel fusion protein and a dual-targeting agent that neutralizes both VEGF and PlGF proangiogenic activities. GRP78 dual effect in tumor growth and a...

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Detalles Bibliográficos
Autores principales: Taghizadeh, Sepideh, Soheili, Zahra-Soheila, Sadeghi, Mehdi, Samiei, Shahram, Ranaei Pirmardan, Ehsan, Kashanian, Ali, Zakeri, Fahimeh, Latifi-Navid, Hamid, Shams Najafabadi, Hoda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8135984/
https://www.ncbi.nlm.nih.gov/pubmed/34011277
http://dx.doi.org/10.1186/s12860-021-00367-5

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