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Modeling clonal structure over narrow time frames via circulating tumor DNA in metastatic breast cancer

BACKGROUND: Circulating tumor DNA (ctDNA) offers minimally invasive means to repeatedly interrogate tumor genomes, providing opportunities to monitor clonal dynamics induced by metastasis and therapeutic selective pressures. In metastatic cancers, ctDNA profiling allows for simultaneous analysis of...

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Detalles Bibliográficos
Autores principales:	Weber, Zachary T., Collier, Katharine A., Tallman, David, Forman, Juliet, Shukla, Sachet, Asad, Sarah, Rhoades, Justin, Freeman, Samuel, Parsons, Heather A., Williams, Nicole O., Barroso-Sousa, Romualdo, Stover, Elizabeth H., Mahdi, Haider, Cibulskis, Carrie, Lennon, Niall J., Ha, Gavin, Adalsteinsson, Viktor A., Tolaney, Sara M., Stover, Daniel G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8136103/ https://www.ncbi.nlm.nih.gov/pubmed/34016182 http://dx.doi.org/10.1186/s13073-021-00895-x

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